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Emerging evidences indicate a new role of TFPI in cancer biology. We recently reported that both isoforms of TFPI induced apoptosis and inhibited proliferation of cancer cells. The signaling pathway(s) mediating the effects of TFPI is, however, presently still unclear. Our goal was to further invest...
ORGANISM(S): Homo sapiens 
Atlantic cod (~70 g) were exposed to water temperatures of 12 and 17 degrees Celsius (flow-through system), then half the fish in each temperature group were infected with Francisella noatunensis (injection). Fish were sampled prior to temperature challenge, when water temp reached 17 degrees, and f...
ORGANISM(S): Gadus morhua 
RNA-seq dataset used to compare the transcriptome of the Atlantic salmon (Salmo salar) tongue and olfactory rosette, in control and infected fish (Yersinia ruckeri). Tongue samples from control also used to describe gene expression in the salmon tongue.
ORGANISM(S): Salmo salar 
Investigate the role of the salmon (Salmo salar) tongue as a potential first-line immune organ by describing the tongues genetic response to an in vivo infection by the bacterial pathogen Yersinia ruckeri.
ORGANISM(S): Salmo salar 
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