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TranscriptomicsRocaglamide A converts RNA helicase eIF4A into a sequence-specific translational repressor
Rocaglamide A (RocA) typifies a novel class of protein synthesis inhibitors that selectively kill aneuploid tumor cells and repress translation of specific mRNAs. RocA targets eukaryotic initiation factor 4A (eIF4A), the prototypical DEAD-box RNA helicase, and its mRNA selectivity is proposed to ref...
ORGANISM(S): synthetic construct 
2016-06-15 | E-GEOD-70211 | biostudies-arrayexpress
TranscriptomicsRocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor
Rocaglamide A (RocA) typifies a class of protein synthesis inhibitors that selectively kill aneuploid tumor cells and repress translation of specific mRNAs. RocA targets eukaryotic initiation factor 4A (eIF4A), an ATP-dependent DEAD-box RNA helicase; its mRNA selectivity is proposed to reflect highl...
ORGANISM(S): synthetic construct 
2016-06-15 | E-GEOD-79392 | biostudies-arrayexpress
UnknownThe Impact of a Nitric Oxide Synthase Inhibitor (L-NAME) on Ischemia⁻Reperfusion Injury of Cholestatic Livers by Pringle Maneuver and Liver Resection after Bile Duct Ligation in Rats.
Not available
S-EPMC6539833 | biostudies-literature
ProteomicsProSeAM SILAC MS screening for METTL18 substrates
Click chemistry based substrates screening for METTL18 in Mettl18 KO HEK293T cells.
ORGANISM(S): Homo Sapiens (human) 
2022-06-09 | PXD026813 | JPOST Repository
ProteomicsLC-MS/MS analysis of pancreatic proteins from WT and Mettl18 KO mice
Label-free quantification of pancreatic proteins from WT and Mettl18 KO mice.
ORGANISM(S): Mus Musculus (mouse) 
2026-02-18 | PXD065601 | JPOST Repository
ProteomicsAnalysis of Mettl1 interacting proteins in Drosophila
Mass spec analysis was performed to identify interacting proteins with FLAG-tagged Mettl1 in Drosophila ovary.
ORGANISM(S): Drosophila Melanogaster (fruit Fly) 
2024-08-20 | PXD044501 | JPOST Repository
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