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This model relates to figure 5 in Bhalla US, Iyengar R. Chaos (2001) 11(1):221-226. It includes the model used for figures 2-4 and also has MKP-1 induction by MAPK activity in the synapse. PP2A is set to 0.16 uM and MKP synthesis is varied from 5x to 40 x basal to get a range of interesting behaviou...
2005-01-01 | MODEL9071773985 | BioModels
For the identification of potential pathways and their interactions that underlie a complex change in cellular state, such as neurite outgrowth, we stimulated the neuroblastoma cell line N2A with HU210, a potent activator of the cannabinoid receptor type I, followed by transcriptomic and proteomic a...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-14 | PXD036706 | Pride
The shape of a cell within tissues can represent the history of chemical and physical signals that it encounters, but can information from cell shape regulate cellular phenotype independently? Using optimal control theory to constrain reaction-diffusion schemes that are dependent on different surfac...
ORGANISM(S): Homo sapiens (Human) 
2018-07-26 | PXD008150 | Pride
Neves2008 - Role of cell shape and size in controlling intracellular signalling The role of cell shape and size in the flow of spatial information from the cell surface receptor to downstream components within the cell has been studied on the β-adrenergic receptor to MAPK-signallin...
2024-09-02 | BIOMD0000000182 | BioModels
Spinal Cord Injury regulates circular mRNA expression in axons

The Family Investigation of Nephropathy and Diabetes (FIND) is a multicenter study designed to identify genetic determinants of diabetic kidney disease. Study subjects were recruited from eleven centers and in many ethnic groups throughout the United States. A genome-wide association stu...

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