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ProteomicsLabel-free quantification of NMT1 and NMT2 knockout as well as PCLX-001 treated HAP1 cells
HAP1 cells with an NMT1, NMT2, or double knockout (as well as wildtype controls) were prepared by in-gel trypsin digestion and analyzed by LC-MS/MS label-free quantification (data-dependent acquisition). Additionally, HAP1 cells were treated with PCLX-001, an NMT inhibitor, at EC50 and EC90 (as well...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-05-10 | MSV000091913 | MassIVE
TranscriptomicsSIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing [CLIP-Seq]
SIRT7 is an NAD+-dependent protein deacetylase with important roles in ribosome biogenesis and cell proliferation. Previous studies have established that SIRT7 is associated with RNA polymerase I, interacts with pre-rRNA and promotes rRNA synthesis. Here we show that SIRT7 is also associated with sn...
ORGANISM(S): Homo sapiens 
2016-01-07 | E-GEOD-76578 | biostudies-arrayexpress
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