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GenomicsEctopseudomonas alcaliphila JAB1
Ectopseudomonas alcaliphila JAB1 Genome sequencing
PRJNA104953 | ENA
TranscriptomicsMCF10A_MYC_PLUS_CSN5
Gene expression signatures encompassing dozens to hundreds of genes have been associated with many important parameters of cancer, but mechanisms of their control are largely unknown. Here we present a method based on genetic linkage that can prospectively identify functional regulators driving larg...
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-2824 | biostudies-arrayexpress
GenomicsThe p53-dependent role of JAB1 in OS pathogenesis
The p53-dependent role of JAB1 in OS pathogenesis
PRJNA483169 | ENA
GenomicsEssential role of Jab1 in mouse chondrocyte differentiation.
Essential role of Jab1 in mouse chondrocyte differentiation.
PRJNA599392 | ENA
GenomicsEssential role of JAB1 in human chondrosarcoma pathogenesis
Essential role of JAB1 in human chondrosarcoma pathogenesis
PRJNA566202 | ENA
GenomicsJAB1/CRL4B Complex Represses PPARG/ACSL5 Expression to Promote Breast Tumorigenesis
JAB1/CRL4B Complex Represses PPARG/ACSL5 Expression to Promote Breast Tumorigenesis
PRJNA1216176 | ENA
TranscriptomicsThe p53-dependent role of JAB1 in OS pathogenesis
JAB1 is a regulator of ubiquitin mediated protein degradation upstream of the 26S proteasome. JAB1 regulates the ubiquitin proteasome system through controlling the activity of the largest family of E3 ubiquitin ligases, the Cullin-RING Ligases. JAB1 is also a transcriptional co-factor contolling th...
ORGANISM(S): Homo sapiens 
2020-06-10 | GSE117773 | GEO
TranscriptomicsJAB1/CRL4B Complex Represses PPARG/ACSL5 Expression to Promote Breast Tumorigenesis
Fatty acid metabolism is critical for tumor progression, supplying bioenergetic and biosynthetic substrates to rapidly proliferating cancer cells. However, the precise mechanisms by which fatty acid metabolism influences breast cancer progression remain unclear. In this study, we aimed to explore th...
ORGANISM(S): Homo sapiens 
2026-06-18 | GSE288090 | GEO
GenomicsEffect of Jab1 knockdown on gene expression during disease progression in acute myeloid leukemia
Effect of Jab1 knockdown on gene expression during disease progression in acute myeloid leukemia
PRJNA1069643 | ENA
TranscriptomicsEffect of Jab1 knockdown on gene expression during disease progression in acute myeloid leukemia
The progression of acute myeloid leukemia (AML) is a complex process involving various cellular activities. In this context, our research focuses on the role of Jab1 as a key regulatory factor. Specifically, Jab1 plays a crucial role in regulating apoptosis and proliferation, providing support for t...
ORGANISM(S): Homo sapiens 
2025-07-17 | GSE254292 | GEO
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