Sort   by:  
 Page size 
TranscriptomicsReference: MicroRNA expression profiling in adult mouse liver following BaP treatment [Agilent miRNA array]
We have investigated the effect of exposure to 150 mg/kg benzo(a)pyrene (BaP) for 3 days on mRNA and miRNA expression levels in adult mouse liver. We used Agilent miRNA array platforms to assess effects of BaP exposure on miRNA expression levels. Our results indicate a distinct lack of effect of BaP...
ORGANISM(S): Mus musculus 
2010-10-28 | E-GEOD-19438 | biostudies-arrayexpress
TranscriptomicsAdult mouse liver following benzo(a)pyrene (BaP) treatment: miRNA and mRNa profiling
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2010-10-18 | E-GEOD-18841 | biostudies-arrayexpress
GenomicsMRC HGU IGMM Edinburgh DAC
Data Access Committee EGAC00001000393
EGAC00001000393 | EGA
TranscriptomicsmRNA expression profiling in adult mouse liver following benzo(a)pyrene (BaP) treatment [Agilent gene expression array]
Adult male mice were exposed to 150 mg/kg benzo(a)pyrene (BaP) or solvent for 3 days and sampled 4 or 24 hours after the last dose. mRNA expression levels in adult mouse liver were measured using Agilent arrays. We found widespread changes in mRNA in pathways consistent with known response (xenobiot...
ORGANISM(S): Mus musculus 
2010-10-18 | E-GEOD-18789 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profiling in adult mouse liver following benzo(a)pyrene (BaP) treatment [Exiqon miRNA array]
Lack of change in microRNA expression in adult mouse liver following treatment with benzo(a)pyrene (BaP), as detected using Exiqon miRNA arrays. Adult male mice were exposed to 150 mg/kg benzo(a)pyrene (BaP) or solvent for 3 days and sampled 4 hours after the last dose. MicroRNA expression levels in...
ORGANISM(S): Mus musculus 
2010-10-18 | E-GEOD-18782 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human lymphatic endothelial cells, mouse dermal cells and human skin cells reveals an inflammation-induced mechanism for leukocyte transmigration of lymphatic vessel endothelium.
The exit of antigen-presenting cells (APC) and lymphocytes from inflamed skin to afferent lymph is vital for the initiation and maintenance of dermal immune responses. How such exit is achieved and how cells transmigrate the distinct endothelium of lymphatic vessels is however unknown. Here we show ...
ORGANISM(S): Homo sapiens 
2008-11-07 | E-GEOD-6257 | biostudies-arrayexpress
TranscriptomicsAcute hepatic transcriptional response in male mice following oral exposure to benzo(a)pyrene
Benzo(a)pyrene is a well-established human carcinogen in humans and rodents. In the present study, we sought to determine the dose- and time-dependent changes in gene expression upon oral exposure to benzo(a)pyrene. Adult male B6C3F1 mice were exposed to four doses of benzo(a)pyrene or vehicle contr...
ORGANISM(S): Mus musculus 
2015-07-01 | E-GEOD-43633 | biostudies-arrayexpress
TranscriptomicsThe effect of BrdU on gene expression profiles of B6C3F1 mice treated with furan
Furan is a mouse and rat hepatocarcinogen. We sought to determine the dose-dependent changes in gene expression upon exposure of B6C3F1 mice to furan in order to better understand furan’s mode of action. In this study we examined the transcriptional response in liver tissue of female B6C3F1 mice to ...
ORGANISM(S): Mus musculus 
2014-07-01 | E-GEOD-54078 | biostudies-arrayexpress
TranscriptomicsCell death and regenerative proliferation pathways in hepatocellular carcinoma: The effect of furan on B6C3F1 mouse global gene expression in liver
Furan is a mouse and rat hepatocarcinogen. We sought to determine the dose-dependent changes in gene expression upon exposure of B6C3F1 mice to furan in order to better understand furan’s mode of action. Adult female B6C3F1 mice were exposed to 1, 2, 4 or 8 mg/kg bw furan or vehicle control (corn oi...
ORGANISM(S): Mus musculus 
2014-01-10 | E-GEOD-48644 | biostudies-arrayexpress
Genomicsena-DATASET-MRCHGUIGMM-07-10-2015-09:16:27:050-356 - samples
BAM files for two WES TRAIP patients
EGAD00001001633 | EGA
Sort   by:  
 Page size