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We compared the molecular specificities of tumours developed in Ukrainian subjects exposed or not to radioiodines during the Chernobyl accident. Exposed subjects are associated with estimated high thyroid doses (0.58 to 4.5 Gy) known to be associated with an increased risk of developing radiation-in...
ORGANISM(S): Homo sapiens 
RNA sequencing was performed on sorted populations of Lgr6-positive and Lgr6-negative keratinocytes from the interfollicular epidermis and the hair follicle/sebaceous gland, in order to determine the compartment-specific expression signatures of Lgr6+ progenitor cells.
ORGANISM(S): Mus musculus 
The goals of this study is to analyse transcriptionnal changes in senescent cells and to compare them with ChIPseq data for several histones marks and proteins of the SUMO machinery mRNA profiling of proliferative versus Ras-induced senescent humain primary fibroblasts 5 days post-infection
ORGANISM(S): Homo sapiens 
Transcription factors represent one of the largest groups of proteins regulated by SUMO, and their modification has generally been correlated with transcriptional repression. However, as most of the studies focus on specific sumoylated transcriptional regulators, the distribution and global role of ...
ORGANISM(S): Homo sapiens 
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