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TranscriptomicsJagged1 regulates miRNA expression profile
miRNA expression profiles of HMECs treated with 40mM Jagged1 (JAG1) or the control peptide for 1 day Genome-wide miRNA PCR array analysis was performed using human miRNA PCR arrays (MIHS216Z, SABiosceinces) acccording to the manufacturer's instructions
ORGANISM(S): Homo sapiens 
2014-05-30 | E-GEOD-56801 | biostudies-arrayexpress
TranscriptomicsTumor-derived Jagged1- and Notch-dependent transcription changes in MC3T3-E1 osteoblasts
Transcriptional profiling of MC3T3-E1 osteoblasts that were flow cytometry-separated from cocultures with control or Jagged1-overexpressing tumor cells and treated with either DMSO control or 1μM MRK-003 (gamma-secretase inhibitor). One cell line (MC3T3-E1) cells: four different experimental conditi...
ORGANISM(S): Mus musculus 
2010-08-15 | E-GEOD-20517 | biostudies-arrayexpress
TranscriptomicsThe downstream molecules of Notch signaling in vascular endothelial cell senescence
To further investigate the mechanism how the decline in Notch signaling induces premature senescence in endothelial cells, we performed microarray analysis and identified Id1 nd DUSP1 as the downstream molecules of Notch pathway. In quantitative PCR and western blot analyses, the expression level of...
ORGANISM(S): Homo sapiens 
2012-08-28 | E-GEOD-40403 | biostudies-arrayexpress
GenomicsThe Notch ligand Jagged1 regulates extracellular matrix production and organization in triple-negative breast cancer
The Notch ligand Jagged1 regulates extracellular matrix production and organization in triple-negative breast cancer
PRJNA1261943 | ENA
OtherJagged1 regulates miRNA expression profile
miRNA expression profiles of HMECs treated with 40mM Jagged1 (JAG1) or the control peptide for 1 day
ORGANISM(S): Homo sapiens 
2014-05-30 | GSE56801 | GEO
UnknownInhibition of HER2 Increases JAGGED1-dependent Breast Cancer Stem Cells: Role for Membrane JAGGED1.
Not available
S-EPMC6139046 | biostudies-literature
TranscriptomicsDifferential gene expression in Jagged1 treated human dental pulp cells.
The present study aimed to determine mRNA expression profilling of indirect immobilized Jagged1 treated human dental pulp cells. Human dental pulp cells were seeded on indirect immobilized Jagged1 surface for 24 h. Cells on hFc immobilized surface was employed as the control. RNA sequencing was perf...
ORGANISM(S): Homo sapiens 
2017-04-04 | GSE94989 | GEO
Genomicsβ-cell Jagged1 is sufficient but not necessary for islet Notch activity and insulin secretory defects.
β-cell Jagged1 is sufficient but not necessary for islet Notch activity and insulin secretory defects.
PRJNA1047593 | ENA
GenomicsJAGGED1 Promotes Tumor Progression through Recruitment of Macrophages and Functional Suppression of Tumor-killing T cells [RNA-seq]
JAGGED1 Promotes Tumor Progression through Recruitment of Macrophages and Functional Suppression of Tumor-killing T cells [RNA-seq]
PRJNA679319 | ENA
GenomicsJAGGED1 Promotes Tumor Progression through Recruitment of Macrophages and Functional Suppression of Tumor-killing T cells [scRNA-seq]
JAGGED1 Promotes Tumor Progression through Recruitment of Macrophages and Functional Suppression of Tumor-killing T cells [scRNA-seq]
PRJNA679322 | ENA
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