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UnknownInhibition of CaMKK2 reverses age-associated decline in bone mass.
Not available
S-EPMC4737584 | biostudies-literature
TranscriptomicsThe zinc finger protein Mig1 regulates mitochondrial function and azole drug susceptibility in the pathogenic fungus Cryptococcus neoformans
The opportunistic pathogen Cryptococcus neoformans causes fungal meningoencephalitis in immunocompromised individuals. In previous studies, we found that the Hap complex in this pathogen represses genes encoding mitochondrial respiratory functions and TCA cycle components under low-iron conditions....
ORGANISM(S): Cryptococcus neoformans 
2015-12-17 | E-GEOD-76063 | biostudies-arrayexpress
TranscriptomicsIL-8 Confers Acquired Resistance to EGFR Inhibitors through Regulating Stem Cell-like Properties in Lung Cancer
Previous study has demonstrated that PC9/gef cells are resistant to gefitinib-induced aspoptosis. To investigate the regulators contributed to gefitinib resistance in lung cancer, we analyzed the gene expression profiles between PC9 and PC9/gef cells. Our results showed that IL-8 contributes to gefi...
ORGANISM(S): Homo sapiens 
2015-08-12 | E-GEOD-60189 | biostudies-arrayexpress
TranscriptomicsBreaking endodormancy in leafy spurge crown buds by dehydration-stress and vernalization identifies overlapping molecular networks linked to growth regulators
Persistence of the invasive perennial weed leafy spurge is mainly attributed to seasonal production of underground adventitious buds (UABs), which undergo well-defined phases of dormancy (para-, endo- and eco-dormancy). These well-defined phases of dormancy also allow UABs of leafy spurge to survive...
ORGANISM(S): Euphorbia esula 
2011-04-05 | E-GEOD-28047 | biostudies-arrayexpress
TranscriptomicsCSF2 x gender interactions on the transcriptome of Day 15 bovine extra-embryonic membrane
We aimed to study the effects of CSF2 treatment on the transcriptome of the Day 15 female and male embryo. Within the raw files, channel 1= Cy3 and channel 2= Cy5 Transcriptional profiling of bovine extra-embryonic membrane at Day 15 post-insemination produced by IVF. Oocytes were matured and ferti...
ORGANISM(S): Bos taurus 
2014-10-01 | E-GEOD-55364 | biostudies-arrayexpress
TranscriptomicsDifferentially expressed microRNAs revealed by molecular signatures of Preeclampsia and IUGR in human placenta
The placenta plays an important role as a regulator of fetal nutrition and growth throughout development and placental factors contribute to gestational abnormalities such as preeclampsia. This study describes the genome-wide gene expression profiles of a large (n=94) set of human placentas in order...
ORGANISM(S): Homo sapiens 
2012-02-07 | E-GEOD-35574 | biostudies-arrayexpress
UnknownOncological Follow-up Strategies for Testicular Germ Cell Tumours: A Narrative Review.
Not available
S-EPMC9465095 | biostudies-literature
TranscriptomicsTranscriptional profiling of six normal Angus tissues
Transcriptional profiling of six bovine tissues (small intestine, spleen, liver, adrenal gland, anterior pituitary, and thymus). Samples collected from each of 6 Angus steers at 14 months of age. Experiment was duplicated at two locations to measure reproducability of results. Six tissues, six biolo...
ORGANISM(S): Bos taurus 
2010-11-01 | E-GEOD-23837 | biostudies-arrayexpress
TranscriptomicsEffect of sexual recombination on population diversity in aflatoxin production by Aspergillus flavus and evidence for cryptic heterokaryosis
Aspergillus flavus is the major producer of carcinogenic aflatoxins in crops worldwide. Natural populations of A. flavus show tremendous variation in aflatoxin production some of which can be attributed to extreme environmental conditions (e.g., drought), differential regulation of the aflatoxin bi...
ORGANISM(S): Aspergillus flavus 
2012-03-07 | E-GEOD-27484 | biostudies-arrayexpress
TranscriptomicsTranscriptome Sequence Analysis of Pediatric Acute Megakaryoblastic Leukemia Identifies An Inv(16)(p13.3;q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein As a Recurrent Lesion in 39% of Non-Infant Cases [2010]
Transcriptome Sequence Analysis of Pediatric Acute Megakaryoblastic Leukemia Identifies An Inv(16)(p13.3;q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein As a Recurrent Lesion in 39% of Non-Infant Cases:  A Report From the St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Gen...
ORGANISM(S): Homo sapiens 
2012-11-20 | E-GEOD-35202 | biostudies-arrayexpress
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