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...fice of Cancer Genomics at the National Cancer Institute is sponsoring a series of studies as part of the Cancer Genome Characterization Initiative (CGCI) to assess novel emerging sequencing technologies in cancer. The CGCI program includes comprehensive characterization of the genetic aberrations...
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...INTRODUCTION: Myxomatous mitral valve disease (MMVD) is the most common cardiac condition in adult dogs. The disease progresses over several years and affected dogs may develop congestive heart failure (HF). Research has shown that myocardial metabolism is altered in cardiac disease,...
2022-03-31 | MTBLS716 | MetaboLights
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<b>Startup of Framingham Heart Study. Cardiovascular disease (CVD) is the leading cause ...
... Cohort, please click on the "Variables" tab above.

The Framingham Cohort is utilized in the following dbGaP substudies. To view genotypes, analysis, expression data, other molecular data, and derived variables collected in these substudies, please click on the following substudies below or in the "Substudies" box located on the right hand side of this top-level study page phs000007 Framingham Cohort.

The unflagging commitment of the research participants in the NHLBI FHS has made more than a half century of research success possible. For decades, the FHS has made its data and DNA widely available to qualified investigators throughout the world through the Limited Access Datasets and the FHS DNA Committee, and the SHARe database will continue that tradition by allowing access to qualified investigators who agree to the requirements of data access. With the SHARe database, we continue with an ambitious research agenda and look forward to new discoveries in the decades to come.

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The goal of the study is to find susceptibility genes for schizophrenia.

Dataset versioning

  • Version 1: European-American (EA) ancestry only
  • Version 2: Version 1 plus African-American (AA) ancestry

Consent groups and pa...

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Genetics of Kidneys in Diabetes (GoKinD) study is an initiative aimed at identifying susceptibility genes for dia...
...other parents and the remaining cases and controls are available by a separate application process through NIDDK (dbGaP phs000088 Search for Susceptibility Genes for Diabetic Nephropathy in Type 1 Diabetes (GoKinD study participants and parents), NIDDK). Interested investigators may request the DNA collection and corresponding clinical data for GoKinD participants using the instructions and application form available at Juvenile Diabetes Research Foundation.

Consent groups and partici...

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Cases with Type 1 Diabetes (T1D) in the UK, were part of the Wellcome Trust Case Control Consortium (WTCCC) ...
...get="_blank">19430480.

Resources - data:

* Case data from this study is deposited here (i.e. in dbGaP)

* Control data from this experiment - with subjects from the 1958 British Birth Cohort - is deposited with the European Genotype Archive (EGA):

http://www.ebi.ac.uk/ega/

from where the WTCCC data is also available.

* A complete description of how to request all components of the meta-analysis is available at:

http://www.t1dbase.org/page/PosterView/display/poster_id/324

* Additional genetic data on the same case subjects, including some HLA types, are available from the Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory (JDRF/WT-DIL):

http://www-gene.cimr.cam.ac.uk/todd/

Resources - samples:

Case and control DNA samples are also available:

* Case DNA samples are available from the JDRF/WT-DIL, as above, and will be available from the NIDDK Genetic...

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The Jackson Heart Study (JHS) is a large, community-based, observational study whose participants were recruited from urban and rural area...
...ts: ARIC, CARDIA, CFS, JHS, and MESA. Data from individual cohorts is available to approved investigators through dbGaP.

Some relevant CARe publications
CARe Study: PMID 20400780
CVD Chip Design: PMID 18974833

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Not available
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The Women's Health Initiative (WHI) is a long-term national health study that has focused on strategies for preventing heart disease, breast and colorectal cancer, and osteoporotic fractures in postmenopausal women. The o...
..., height, weight, waist circumference, grip strength, etc).

The WHI Cohort is utilized in the following dbGaP substudies. To view genotypes, analysis, expression data, other molecular data, and derived variables collected in these substudies, please click on the following substudies below or in the "Substudies" box located on the right hand side of this top-level study page phs000200 WHI Cohort.

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The Atherosclerosis Risk in Communities (ARIC) Study, sponsored by the National Heart, Lung and Blood Institute (NHLBI), is a prospective epidemiologic...
...ts: ARIC, CARDIA, CFS, JHS, and MESA. Data from individual cohorts is available to approved investigators through dbGaP.

Some relevant CARe publications
CARe Study: PMID 20400780
CVD Chip Design: PMID 18974833

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