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TranscriptomicsVDJ: Single-cell RNA sequencing of human steady-state immune cells from the lamina propria of colon and matching mesenteric lymph nodes
The human colon contains an extensively diverse microbial ecosystem and one of the most numerous communities of immune cells. Studies have highlighted dynamic crosstalk between immune cells and commensals. While studies have demonstrated increasing diversity of microbiota from stomach to stool, whe...
ORGANISM(S): Homo sapiens 
2020-01-01 | E-MTAB-8476 | biostudies-arrayexpress
TranscriptomicsGEX: Single-cell RNA sequencing of human steady-state immune cells from the lamina propria of colon and matching mesenteric lymph nodes
The human colon contains an extensively diverse microbial ecosystem and one of the most numerous communities of immune cells. Studies have highlighted dynamic crosstalk between immune cells and commensals. While studies have demonstrated increasing diversity of microbiota from stomach to stool, whe...
ORGANISM(S): Homo sapiens 
2020-01-01 | E-MTAB-8474 | biostudies-arrayexpress
TranscriptomicsSS2_1: Single-cell RNA sequencing of human steady-state immune cells from the lamina propria of colon and matching mesenteric lymph nodes
The human colon contains an extensively diverse microbial ecosystem and one of the most numerous communities of immune cells. Studies have highlighted dynamic crosstalk between immune cells and commensals. While studies have demonstrated increasing diversity of microbiota from stomach to stool, whe...
ORGANISM(S): Homo sapiens 
2020-01-01 | E-MTAB-8484 | biostudies-arrayexpress
TranscriptomicsSS2_2: Single-cell RNA sequencing of human steady-state immune cells from the lamina propria of colon and matching mesenteric lymph nodes
The human colon contains an extensively diverse microbial ecosystem and one of the most numerous communities of immune cells. Studies have highlighted dynamic crosstalk between immune cells and commensals. While studies have demonstrated increasing diversity of microbiota from stomach to stool, whe...
ORGANISM(S): Homo sapiens 
2020-01-01 | E-MTAB-8486 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA sequencing of human steady-state immune cells from the lamina propria of colon and matching mesenteric lymph nodes
The human colon contains an extensively diverse microbial ecosystem and one of the most numerous communities of immune cells. Studies have highlighted dynamic crosstalk between immune cells and commensals. While studies have demonstrated increasing diversity of microbiota from stomach to stool, whe...
ORGANISM(S): Homo sapiens 
2020-01-01 | E-MTAB-8007 | biostudies-arrayexpress
TranscriptomicsThe human gastrointestinal tract through space and time- Adult VDJ
Using single-cell RNAseq (scRNAseq) and paired VDJ analysis, we create the first comprehensive cell atlas of the healthy developing, paediatric and adult human gut, including 347,980 cells from up to 10 distinct anatomical sites. We use this data to trace the cellular composition of the gut througho...
ORGANISM(S): Homo sapiens 
2021-09-13 | E-MTAB-9532 | biostudies-arrayexpress
TranscriptomicsSingle-cell sequencing of developing human gut reveals transcriptional links to childhood Crohn’s disease
In this study, we performed single-cell transcriptional profiling of human embryonic and fetal gut samples obtained from 9 human embryos spanning ages 6-10 PCW and three regions (duo-jejunum, ileum and colon). Additionally, we profile mucosal biopsies from the terminal ileum of healthy children aged...
ORGANISM(S): Homo sapiens 
2020-12-22 | E-MTAB-8901 | biostudies-arrayexpress
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