Sort   by:  
 Page size 
MetabolomicsMetabolic profiling of prostate cancer in skeletal microenvironments identifies G6PD as a key mediator of growth and survival

The spread of cancer to bone is invariably fatal, with complex cross-talk between tumor cells and the bone microenvironment responsible for driving disease progression. By combining in silico analysis of patient datasets with metabolomic profiling of prostate cancer cells cultured with bone cells...

2024-08-19 | MTBLS3973 | MetaboLights
TranscriptomicsExpression analysis of laser-dissected SNpc neurons in Parkinson's disease
Genome-wide transcriptome analysis of expression changes in laser-dissected SNpc neurons from Parkinson's disease brain tissue versus control brain tissue. Post-mortem brain expression analysis performed in 10 PD brain samples and 8 control brain samples.
ORGANISM(S): Homo sapiens 
2010-02-22 | E-GEOD-20141 | biostudies-arrayexpress
TranscriptomicsWhole-genome gene expression profiles of non-tumorous human lung tissues: UBC set
We profiled genome-wide gene expression in non-tumorous human lung tissues. The overall goal of this project is to improve our molecular understanding of various lung diseases including lung cancer and chronic obstructive pulmonary disease (COPD). The samples from the University of British Columbia ...
ORGANISM(S): Homo sapiens 
2012-06-10 | E-GEOD-23529 | biostudies-arrayexpress
GenomicsTGF-β attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells.
We examined tumours from a large cohort of patients with metastatic urothelial bladder cancer (mUC) treated with an anti–PD-L1 agent (atezolizumab) and identified major determinants of clinical response and immune escape. Whole transcriptome profiles were generated for 368 patients using TruSeq RNA ...
EGAS00001002556 | EGA
TranscriptomicsTranscriptional analysis of prefrontal area 9 in Parkinson's disease
Post mortem tissue was dissected from two groups of age and gender matched groups of Parkinson and Control subjects Published work contains more information on Parkinson and Control groups
ORGANISM(S): Homo sapiens 
2010-02-22 | E-GEOD-20168 | biostudies-arrayexpress
TranscriptomicsSystematic meta-analysis and replication of genome-wide expression studies of Parkinson's disease: 2
Systematic meta-analysis and replication of genome-wide expression studies identifies molecular pathways of Parkinson's disease. Examination of substantia nigra from postmortem brains of 8 patients with Parkinson's disease (PD). The substantia nigra samples from 8 PD subjects were obtained from the ...
ORGANISM(S): Homo sapiens 
2011-01-20 | E-GEOD-20163 | biostudies-arrayexpress
UnknownAnti-CTLA-4 generates greater memory response than anti-PD-1 via TCF-1.
Not available
S-EPMC11745370 | biostudies-literature
MetabolomicsEx-Vivo Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study
Osteoarthritis (OA) is an age-related degenerative musculoskeletal disease characterised by loss of articular cartilage, synovitis, abnormal bone proliferation and subchondral bone sclerosis. Underlying OA pathogenesis is yet to be fully elucidated with no OA specific biomarkers in clinical use. Ex-...
2020-09-30 | MTBLS1495 | MetaboLights
UnknownClinical characterization of colitis arising from anti-PD-1 based therapy.
Not available
S-EPMC6287774 | biostudies-literature
UnknownSerum Total 25-OH Vitamin D Adds Little Prognostic Value in Patients Undergoing Coronary Catheterization.
Not available
S-EPMC5121522 | biostudies-literature
Sort   by:  
 Page size