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UnknownPhotoinduced Electron Transfer in a Radical SAM Enzyme Generates an S-Adenosylmethionine Derived Methyl Radical.
Not available
S-EPMC6901192 | biostudies-literature
MetabolomicsRegional HNSCC metabolomics reveals widespread changes to one-carbon metabolism and S-adenosylmethionine metabolism across tumour core, tumour edge and adjacent non-tumour tissues

Cancer, including head and neck squamous cell carcinoma (HNSCC), induces changes to metabolism that drive the disease. Regional metabolomics can help to understand metabolic variation across the tumour including changes near the tumour core, where hypoxia is likely more pronounced. We apply ultra...

2026-06-03 | MTBLS1905 | MetaboLights
UnknownCryo-EM structure of a 40 kDa SAM-IV riboswitch RNA at 3.7 A resolution.
Not available
S-EPMC6890682 | biostudies-literature
UnknownRadical SAM Enzyme Spore Photoproduct Lyase: Properties of the Ω Organometallic Intermediate and Identification of Stable Protein Radicals Formed during Substrate-Free Turnover.
Not available
S-EPMC7730139 | biostudies-literature
GenomicsChIP-seq analysis of H3K9me3 levels across the genome for one copy of H3K9M mutant in pombe
We performed ChIP-seq analyses for WT, H3K9M mutant and clr4 mutant in Schizosaccharomyces pombe, and showed that H3K9me3 level was reduced to background levels across the entire genome, similar to clr4 mutant.
ORGANISM(S): Schizosaccharomyces pombe 
2016-10-03 | E-MTAB-4776 | biostudies-arrayexpress
UnknownThe Resistance Responses of Potato Plants to Potato Virus Y Are Associated with an Increased Cellular Methionine Content and an Altered SAM:SAH Methylation Index.
Not available
S-EPMC8224460 | biostudies-literature
ProteomicsDynamic Assembly of the Cytosolic Iron-Sulfur Cluster Biogenesis Machinery Requires Iron-Sulfur Cluster Incorporation of CIAO3
Cytosolic iron-sulfur (Fe-S) cluster assembly (CIA) pathway delivers Fe-S clusters to nuclear and cytosolic Fe-S proteins involved in essential cellular functions. This delivery process is regulated by availability of iron and oxygen, but it remains unclear how CIA components orchestrate the cluster...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-11-16 | MSV000088394 | MassIVE
ProteomicsIron-Regulated Assembly of the Cytosolic Iron-Sulfur Cluster Biogenesis Machinery
The cytosolic iron-sulfur (Fe-S) cluster assembly (CIA) pathway delivers Fe-S clusters to nuclear and cytosolic Fe-S proteins involved in essential cellular functions. Although the delivery process is regulated by the availability of iron and oxygen, it remains unclear how CIA components orchestrate...
ORGANISM(S): Homo Sapiens 
2022-06-06 | PXD033557 | panorama
ProteomicsAccumulation of acylcarnitines and mitochondrial dysfunction characterize the loss of neonatal myocardial regeneration capacity
Myocardial regeneration capacity declines during the first week after birth and is linked to the adaptation to oxidative metabolism. Utilizing this regenerative window, we characterized the metabolic changes in myocardial injury in 1-day-old regeneration-competent and 7-day-old regeneration-compromi...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-02-04 | MSV000088783 | MassIVE
TranscriptomicsNative versus cultured retinal pigment epithelium cells
I. Exp Design 1. Type of experiment: Comparison of native versus cultured RPE cells 2. Experimental factors: Native RPE versus ARPE-19 cells grown on different matrices 3. How many hybridizations in exp: 21 4. If a common reference used for all the hybs: no 5. Quality control steps: three independen...
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-741 | biostudies-arrayexpress
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