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TranscriptomicsTranscription profiling of human T98G cells during cell cycle in T98G
The mammalian Retinoblastoma (RB) family including pRB, p107, and p130 represses E2F target genes through mechanisms that are not fully understood. In D. melanogaster, RB-dependent repression is mediated in part by the multisubunit protein complex Drosophila RBF, E2F, and Myb (dREAM) that contains h...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-8537 | biostudies-arrayexpress
UnknownIncidence of Medically-Attended Norovirus-Associated Acute Gastroenteritis in Four Veteran's Affairs Medical Center Populations in the United States, 2011-2012.
Not available
S-EPMC4440768 | biostudies-literature
TranscriptomicsTranscription profiling of mouse developing and mature Nrl -/- retina against wild type controls
The rod photoreceptor-specific neural retina leucine zipper protein Nrl is essential for rod differentiation and plays a critical role in regulating gene expression. In the mouse retina, rods account for 97% of the photoreceptors; however, in the absence of Nrl (Nrl-/-), no rods are present and a co...
ORGANISM(S): Mus musculus 
2009-10-30 | E-GEOD-8972 | biostudies-arrayexpress
UnknownUse of the knowledge to action model improved physical therapist adherence to a common clinical practice guideline across multiple settings: a multisite case series.
Not available
S-EPMC9714412 | biostudies-literature
UnknownIschaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
Not available
S-EPMC4255242 | biostudies-literature
GenomicsResponse and resistance to BET bromodomain inhibitors in triple negative breast cancer [ChIP-Seq]
Triple negative breast cancer (TNBC) is a heterogeneous and clinically aggressive disease for which there is no targeted therapy. Here we report the preferential and high sensitivity of TNBCs to BET bromodomain inhibitors such as JQ1 manifested by cell cycle arrest in early G1, apoptosis, and induct...
ORGANISM(S): Homo sapiens 
2016-01-07 | E-GEOD-63581 | biostudies-arrayexpress
TranscriptomicsResponse and resistance to BET bromodomain inhibitors in triple negative breast cancer [RNA-Seq]
Triple negative breast cancer (TNBC) is a heterogeneous and clinically aggressive disease for which there is no targeted therapy. Here we report the preferential and high sensitivity of TNBCs to BET bromodomain inhibitors such as JQ1 manifested by cell cycle arrest in early G1, apoptosis, and induct...
ORGANISM(S): Homo sapiens 
2016-01-07 | E-GEOD-63582 | biostudies-arrayexpress
TranscriptomicsChildhood Onset Rheumatic Disease Gene Expression Profile
Total RNA from peripheral blood mononuclear cells (PBMC) and neutrophils from children with juvenile dermatomyositis (JDM) and juvenile idiopathic arthritis (JIA) were separately compared to pediatric control samples. Keywords: pediatric rheumatic disease, blood, PBMC, neutrophil, JIA, JDM JIA PBMC ...
ORGANISM(S): Homo sapiens 
2009-03-25 | E-GEOD-11083 | biostudies-arrayexpress
GenomicsResponse and resistance to BET bromodomain inhibitors in triple negative breast cancer [Chem-Seq]
Triple negative breast cancer (TNBC) is a heterogeneous and clinically aggressive disease for which there is no targeted therapy. Here we report the preferential and high sensitivity of TNBCs to BET bromodomain inhibitors such as JQ1 manifested by cell cycle arrest in early G1, apoptosis, and induct...
ORGANISM(S): Homo sapiens 
2016-01-07 | E-GEOD-63284 | biostudies-arrayexpress
TranscriptomicsReal-time quantitative PCR analysis of hormone-receptor-negative primary breast tumors
Total RNA was extracted from FFPE samples of 139 chemotherapy-naïve hormone-receptor-negative breast cancers pooled from three sample sources and assayed for the expression of 21 genes within two previously reported microarray-derived prognostic signatures in 6 RT-PCR multiplexes. RT-PCR gene expre...
ORGANISM(S): Homo sapiens 
2013-10-25 | E-GEOD-51630 | biostudies-arrayexpress
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