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ProteomicsHUVEC endosome LCMS - ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes
Complement promotes vascular inflammation in transplant organ rejection and connective tissue diseases. Here we identify ZFYVE21 as a complement-induced Rab5 effector that regulates pro-inflammatory non-canonical NF-B signaling in endothelial cells (EC). In response to membrane attack complexes (MAC...
ORGANISM(S): Homo sapiens (Human) 
2019-04-09 | PXD013381 | Pride
Rab5 mac 
TranscriptomicsEffect of Alloantibody and Complement on Endothelial Cells
Examine the possible pro-inflammatory gene effects of alloantibody and complement on endothelial cells Microarray 3 Experiment performed three times on three separate microarrays using three separate HUVEC and PRA donors. In each experiment, there are four groups of HUVEC with three replicates per g...
ORGANISM(S): Homo sapiens 
2013-08-28 | E-GEOD-50112 | biostudies-arrayexpress
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