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UnknownSurvival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab.
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S-EPMC4811023 | biostudies-literature
TranscriptomicsGene expression analysis of Early immature and Late mature T-ALL cell lines
Early immature T-cell acute lymphoblastic leukemias (T-ALLs) account for about 5-10% of pediatric T-ALLs and are associated with poor prognosis. However, the genetic defects that drive the biology of these tumors remain largely unknown. Analysis of microarray gene expression signatures in adult T-AL...
ORGANISM(S): Homo sapiens 
2013-06-18 | E-GEOD-48046 | biostudies-arrayexpress
TranscriptomicsExpression data from Sh2b3 Knock-out NOTCH1-induced leukemias
To formally address the tumor suppressor activity of Sh2b3 in vivo, we tested the interaction between oncogenic NOTCH1 and Sh2b3 loss in a retroviral- transduction bone marrow transplantation model of NOTCH-induced T-ALL Forced expression of activated NOTCH1 in this model typically results in full l...
ORGANISM(S): Mus musculus 
2013-11-06 | E-GEOD-44025 | biostudies-arrayexpress
TranscriptomicsGene Expression Profile of 57 human T-ALL samples collected in human clinical trial E2993 (Marks et al., 2009)
Analysis of microarray gene expression signatures in adult T-ALL demonstrated a high prevalence of early immature leukemias and revealed a close relationship between these tumors and myeloid leukemias. 57 adult T-ALL samples were analyzed
ORGANISM(S): Homo sapiens 
2011-11-05 | E-GEOD-33469 | biostudies-arrayexpress
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