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TranscriptomicsDifferential effects of antofine N-oxide on solid tumor and leukemia cells
We have studied the anti-cancer activities of antofine N-oxide isolated and purified from the medicinal plant Cynanchum vincetoxicum. The compound displays a strong cytotoxic effect on several solid tumor cell lines (glioblastoma, breast carcinoma and lung carcinoma) and on T-cell leukemia. It induc...
ORGANISM(S): Homo sapiens 
2014-09-23 | E-MTAB-1900 | biostudies-arrayexpress
TranscriptomicsIGR_MESSAI_CCRCC_HIF2
The aim of the present study was to investigate the potential role of HIF-2a in regulating RCC susceptibility to natural killer (NK) cell-mediated killing. We demonstrated that the RCC cell line 786-O with mutated VHL was resistant to NK-mediated lysis as compared to the VHL corrected cell line (WT7...
ORGANISM(S): Homo sapiens 
2014-01-11 | E-MTAB-1802 | biostudies-arrayexpress
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