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TranscriptomicsExpression data from sympathetic nervous system of KI Alk F1178L mice
Neuroblastoma is an embryonal neoplasm that remains of dramatic prognosis in its aggressive forms. Activating mutations of the ALK tyrosine kinase receptor have been identified in sporadic and familial cases of this cancer. We generated knock-in mice carrying an F1178L Alk mutation corresponding to ...
ORGANISM(S): Mus musculus 
2014-06-24 | E-GEOD-46584 | biostudies-arrayexpress
TranscriptomicsBeta-catenin status in pediatric medulloblastomas
Medulloblastoma is the most frequent malignant pediatric brain tumor. Considerable efforts are dedicated to identify markers that help to refine treatment strategies. The activation of the Wnt/beta-catenin pathway occurs in 10-15% of medulloblastomas and has been recently described as a marker for f...
ORGANISM(S): Homo sapiens 
2009-02-02 | E-GEOD-12992 | biostudies-arrayexpress
Genomicsena-DATASET-CURIE-LC-04-05-2015-16:47:47:270-89 - samples
Neuroblastoma, a clinically heterogeneous pediatric cancer, is characterized by distinct genomic profiles but few recurrent mutations. As neuroblastoma is expected to have high degree of genetic heterogeneity, study of neuroblastoma's clonal evolution with deep coverage whole-genome sequencing of di...
EGAD00001001356 | EGA
GenomicsInstitut Curie Neuroblastoma Whole Genome Sequencing Diagnosis Relapse
Neuroblastoma, a clinically heterogeneous pediatric cancer, is characterized by distinct genomic profiles but few recurrent mutations. As neuroblastoma is expected to have high degree of genetic heterogeneity, study of neuroblastoma's clonal evolution with deep coverage whole-genome sequencing of di...
EGAS00001001184 | EGA
Transcriptomicsarray-CGH profiling of human neuroblastoma samples obtained from infants included in the INES99.1, INES99.2 and INES99.3 trials
In neuroblastoma (NB), the presence of segmental chromosome alterations (SCA) is associated with a higher risk of relapse, even when occurring together with numerical chromosome alterations (NCA). Furthermore, recent evidence shows that SCAs play a role in tumor progression. In order to analyze the ...
ORGANISM(S): Homo sapiens 
2011-12-07 | E-GEOD-26494 | biostudies-arrayexpress
Genomicsena-DATASET-AMC-11-05-2015-14:58:16:693-185 - samples
The majority of neuroblastoma patients have tumors that initially respond to chemotherapy, but a large proportion of patients will experience therapy-resistant relapses. The molecular basis of this aggressive phenotype is unknown. Whole genome sequencing of 23 paired diagnostic and relapsed neurobla...
EGAD00001001360 | EGA
GenomicsNeuroblastoma relapse trio series from the AMC
The majority of neuroblastoma patients have tumors that initially respond to chemotherapy, but a large proportion of patients will experience therapy-resistant relapses. The molecular basis of this aggressive phenotype is unknown. Whole genome sequencing of 23 paired diagnostic and relapsed neurobla...
EGAS00001001183 | EGA
GenomicsInstitut Curie Neuroblastoma data access Committee
Data Access Committee EGAC00001000319
EGAC00001000319 | EGA
GenomicsAMC Dept. Oncogenomics
Data Access Committee EGAC00001000321
EGAC00001000321 | EGA
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