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GenomicsGlobal mapping of estrogen receptor and histone modifications in breast tumor samples uncovers distinct patterns for aromatase inhibitor resistance
ChIP-seq on primary breast cancer tumor samples for Era, H3K4me3, H3K27me3. Patients had a poor or good outcome after aromatase inhibitor treatment. Differential binding patterns between good and poor outcome patients were identified for each marker, predicting response to treatment comparing ER, H3...
ORGANISM(S): Homo sapiens 
2013-12-05 | E-GEOD-40867 | biostudies-arrayexpress
ProteomicsProfiling of antibodies against prostate cancer xenograft-released proteins
The present study describes a novel xenograft-based biomarker discovery platform and proves its usefulness in the discovery of novel serum markers for prostate cancer (PCa). By immunizing immuno-competent mice with serum from nude mice bearing PCa xenografts, an antibody response against xenograft-d...
ORGANISM(S): Mus musculus 
2011-12-16 | E-GEOD-16220 | biostudies-arrayexpress
MetabolomicsFour layer multi-omics reveals molecular responses to aneuploidy in Leishmania

Aneuploidy causes system-wide disruptions in the stochiometric balances of transcripts, proteins, and metabolites, often resulting in detrimental effects for the organism. The protozoan parasite Leishmania has an unusually high tolerance for aneuploidy, but the molecular and functional consequenc...

2022-09-19 | MTBLS1612 | MetaboLights
MetabolomicsIntegrated genomic and metabolomic profiling of ISC1, an emerging Leishmania donovani population in the Indian subcontinent

Leishmania donovani is the responsible agent for visceral leishmaniasis (VL) in the Indian subcontinent (ISC). The disease is lethal without treatment and causes 0.2 to 0.4 million cases each year. Recently, reports of VL in Nepalese hilly districts have increased as well as VL cases cau...

2022-09-15 | MTBLS1606 | MetaboLights
UnknownReconstructing firm-level interactions in the Dutch input-output network from production constraints.
Not available
S-EPMC9277606 | biostudies-literature
UnknownMolecular EPISTOP, a comprehensive multi-omic analysis of blood from Tuberous Sclerosis Complex infants age birth to two years.
Not available
S-EPMC10667269 | biostudies-literature
TranscriptomicsTranscription profiling of chicken primary bronchus and secondary bronchi on birds vaccinated under various adjuvants and challenged by avian influenza virus H9N2.
Sylvia Reemers: chicken in vivo infection: timecourse, groupI= non immunised non challenged, groupIII= non immunised challenged, groupIV= immunised challenged, groupV= immunised+w/o challenged, groupVII= immunised+Al(OH)3 challenged, groupIX= immunised+CpG challenged Tissue type= Lung1. The aim of t...
ORGANISM(S): Gallus gallus 
2010-04-11 | E-MTAB-136 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of chicken paleopulmonic parabronchi on birds vaccinated under various adjuvants and challenged by avian influenza virus H9N2.
Sylvia Reemers: chicken in vivo infection: timecourse, groupI= non immunised non challenged, groupIII= non immunised challenged, groupIV= immunised challenged, groupV= immunised+w/o challenged, groupVII= immunised+Al(OH)3 challenged, groupIX= immunised+CpG challenged Tissue type= Lung4. The aim of t...
ORGANISM(S): Gallus gallus 
2010-04-01 | E-MTAB-137 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of chicken trachea on birds vaccinated under various adjuvants and challenged by avian influenza virus H9N2.
Sylvia Reemers: chicken in vivo infection: timecourse, groupI= non immunised non challenged, groupIII= non immunised challenged, groupIV= immunised challenged, groupV= immunised+w/o challenged, groupVII= immunised+Al(OH)3 challenged, groupIX= immunised+CpG challenged Tissue type= Upper trachea. The ...
ORGANISM(S): Gallus gallus 
2010-04-01 | E-MTAB-138 | biostudies-arrayexpress
UnknownThe Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids.
Not available
S-EPMC10673892 | biostudies-literature
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