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TranscriptomicsCombined transcriptomics classifier analysis reveals a set of adverse effect genes for use as potential endpoint in effect based screening
Environmental risk assessment relies heavily on the use of bioassays to assess the environmental impact of chemicals. Gene expression is gaining acceptance as a valuable mechanistic endpoint in bioassays and effect-based screening. Data analysis and its results however, are often complex and not dir...
ORGANISM(S): Folsomia candida 
2015-11-09 | E-GEOD-70877 | biostudies-arrayexpress
TranscriptomicsAdaptive differences in gene expression associated with stress tolerance in the soil arthropod Orchesella cincta
Field-selected tolerance to heavy metals has been reported for Orchesella cincta (Arthropoda: Collembola) populations occurring at metal-contaminated mining sites. This tolerance is correlated with heritable increase of metal excretion efficiency; less pronounce cadmium induced growth reduction and,...
ORGANISM(S): Orchesella cincta 
2009-04-01 | E-GEOD-14076 | biostudies-arrayexpress
TranscriptomicsTranscriptional responses of Folsomia candida exposed to polar and apolar narcotizing compounds.
Narcosis or baseline toxicity is the inert toxicity of hydrophobic compounds, supposed to take place at the level of the cellular membranes. Based on the linear relationship between the toxicity (logEC50) and the hydrophobicity (logKow), class I and II narcotizing compounds are recognized, in whic...
ORGANISM(S): Folsomia candida 
2010-02-02 | E-GEOD-19929 | biostudies-arrayexpress
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