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TranscriptomicsTranscriptome analysis Rhinolophus ferrumequinum (Rfe) cells upon poly-I:C transfection
Transcriptome analysis Rhinolophus ferrumequinum (Rfe) cells upon poly-I:C transfection. Rfe cell expressing human ACE2 and TMPRSS2 (Rfe-AT) and a SARS-Cov-2 / BANAL-236 successible clonal Rfe-AT cell line (Rfe-ATC) were transfected with poly-I:C or PBS and transcriptome was analysed using RNA seque...
ORGANISM(S): Rhinolophus ferrumequinum 
2026-04-10 | E-MTAB-16878 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse hypomorphic for ATG16L1 (implicated in Crohns disease) protein expression reveals a key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
Susceptibility to Crohn's disease, a complex inflammatory disease involving the small intestine, is controlled by over 30 loci. One Crohn's disease risk allele is in ATG16L1, a gene homologous to the essential yeast autophagy gene ATG16 (ref. 2). It is not known how ATG16L1 or autophagy contributes ...
ORGANISM(S): Mus musculus 
2008-11-15 | E-GEOD-13512 | biostudies-arrayexpress
GenomicsUK10K RARE CHD
In the UK10K project we propose a series of complementary genetic approaches to find new low frequency/rare variants contributing to disease phenotypes. These will be based on obtaining the genome wide sequence of 4000 samples from the TwinsUK and ALSPAC cohorts (at 6x sequence coverage), and the ex...
EGAS00001000125 | EGA
GenomicsEGAS00001000317-sc-20140326 - samples
The exome sequencing is performed using Agilent SureSelect 50Mb exome v3 and Hiseq 75bp paired reads with an mean sequencing coverage target of 50X.
EGAD00001000799 | EGA
Genomicsuk10k_rare_chd_rel_2012_07_05-sc-20120727 - samples
UK10K_RARE_CHD REL-2012-07-05
EGAD00001000210 | EGA
Genomicsuk10k_rare_chd_rel_2012_01_13-sc-20120611 - samples
UK10K_RARE_CHD REL-2012-01-13
EGAD00001000178 | EGA
Genomicsuk10k_rare_chd_rel_2012_02_22-sc-20120613 - samples
UK10K_RARE_CHD REL-2012-02-22
EGAD00001000192 | EGA
Genomicsuk10k_rare_chd_rel_2013_04_20-sc-20130522 - samples
UK10K_RARE_CHD REL-2013-04-20
EGAD00001000413 | EGA
Genomicsuk10k_rare_chd_rel_2012_11_27-sc-20121218 - samples
UK10K_RARE_CHD REL-2012-11-27
EGAD00001000294 | EGA
GenomicsEGAS00001000185-sc-20140326 - samples
This project aims to study at least 90 exomes from families with congenital heart disease. The samples have been selected in Leuven in collaboration with Koen Devriendt. Ethic approval has been sought for in Leuven, Belgium and a HDMMC agreement for submitting these samples is in place at the WTSI....
EGAD00001000796 | EGA
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