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TranscriptomicsCharacterization of a Lactococcus lactis high-temperature mutant with increased glycolytic flux
Temperature is an important factor affecting biological organisms. We characterize a Lactococcus lactis (L. lactis) ssp. cremoris MG1363 mutant (CS3527) capable of growing better at a higher temperature than its parent. The transcriptomic analysis also revealed widespread down-regulation of genes en...
ORGANISM(S): Lactococcus lactis 
2015-08-26 | E-GEOD-27698 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human urinary superficial transitional cell carcinoma with surrounding carcinoma in situ (CIS) lesions, without surrounding CIS lesions, and muscle invasive carcinoma
The presence of carcinoma in situ (CIS) lesions in the urinary bladder is associated with a high risk of disease progression to a muscle invasive stage. In this study, we used microarray expression profiling to examine the gene expression patterns in superficial transitional cell carcinoma (sTCC) wi...
ORGANISM(S): Homo sapiens 
2007-11-28 | E-GEOD-3167 | biostudies-arrayexpress
TranscriptomicsGenome-wide study of nuclear poly(A) binding protein Nab2p depletion
Polyadenylation of mRNA is a key step in eu- karyotic gene expression. However, despite the ma- jor impact of poly(A) tails on mRNA metabolism, the precise roles of poly(A)-binding proteins (PABPs) in nuclear mRNA biogenesis remain elusive. Here, we demonstrate that rapid nuclear depletion of the S....
ORGANISM(S): Saccharomyces cerevisiae 
2015-08-13 | E-GEOD-65001 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human advanced bladder cancer to predict response and survival following chemotherapy in patients
BACKGROUND; Cisplatin-containing chemotherapy is the standard of care for patients with locally advanced and metastatic transitional cell carcinoma of the urothelium. The response rate is around 50% and tumor derived molecular prognostic markers are needed for estimation of response and survival. ...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-5287 | biostudies-arrayexpress
UnknownHigh expression of GEM and EDNRA is associated with metastasis and poor outcome in patients with advanced bladder cancer.
Not available
S-EPMC4164753 | biostudies-literature
UnknownReply to: Reconciling differences in impact of molecular subtyping on response to cisplatin-based chemotherapy.
Not available
S-EPMC8355314 | biostudies-literature
TranscriptomicsTranscription profiling of human superficial bladder tumours to delineate the expression pattern differences between non-recurring and recurring tumours
Expression profiling of superficial bladder tumours to delineate the expression pattern differences between non-recurring and recurring tumours.
ORGANISM(S): Homo sapiens 
2007-10-04 | E-GEOD-88 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human bladder tumours to construct a tumour stage classifier
Bladder tumours used to construct a tumour stage classifier
ORGANISM(S): Homo sapiens 
2007-09-28 | E-GEOD-89 | biostudies-arrayexpress
ProteomicsSite-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation (part 2)
Small ubiquitin-like modifiers (SUMOs) are post-translational modifications (PTMs) that regulate nuclear cellular processes. Here we used an augmented K0â??SUMO proteomics strategy to identify 40,765 SUMO acceptor sites and quantify their fractional contribution for 6,747 human proteins. Structuralâ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080869 | MassIVE
ProteomicsSite-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation (part 1)
Small ubiquitin-like modifiers (SUMOs) are post-translational modifications (PTMs) that regulate nuclear cellular processes. Here we used an augmented K0â??SUMO proteomics strategy to identify 40,765 SUMO acceptor sites and quantify their fractional contribution for 6,747 human proteins. Structuralâ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-30 | MSV000080812 | MassIVE
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