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UnknownmiRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation.
Not available
S-EPMC5679080 | biostudies-literature
TranscriptomicsNr4a1 and Nr4a3 upregulate cell cycle genes upregulated in the Nkx6.1 beta-cell proliferation pathway
Loss of functional beta-cell mass is a hallmark of Type 1 and Type 2 diabetes, and methods for restoring these cells are needed. Nkx6.1 induces beta-cell proliferation, but the pathway by which Nkx6.1 activates beta-cell expansion has not been defined. Here we demonstrate that Nkx6.1 induces express...
ORGANISM(S): Rattus norvegicus 
2014-02-18 | E-GEOD-55078 | biostudies-arrayexpress
TranscriptomicsNkx6.1 regulates islet beta-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors
Loss of functional beta-cell mass is a hallmark of Type 1 and Type 2 diabetes, and methods for restoring these cells are needed. We have previously reported that overexpression of the homeodomain transcription factor Nkx6.1 in rat pancreatic islets induces beta-cell proliferation and enhances glucos...
ORGANISM(S): Rattus norvegicus 
2014-02-18 | E-GEOD-55077 | biostudies-arrayexpress
UnknownPhysical Activity in 1-Year-Old Children Predicts Physical Activity Level at Age 3 Years Independent of Maternal Activity.
Not available
S-EPMC12547452 | biostudies-literature
UnknownThe Effect of Y Content on Structural and Sorption Properties of A2B7-Type Phase in the La-Y-Ni-Al-Mn System.
Not available
S-EPMC10180221 | biostudies-literature
UnknownCounteracting Age-related Loss of Skeletal Muscle Mass: a clinical and ethnological trial on the role of protein supplementation and training load (CALM Intervention Study): study protocol for a randomized controlled trial.
Not available
S-EPMC4977774 | biostudies-literature
ProteomicsEggerthella lenta DSM 2243 alleviates bile acid stress response in Clostridium ramosum and Anaerostipes cacae by transformation of bile acids
Bile acids are not only crucial for the uptake of lipids, but also have widespread systematic ef-fects and shape the gut-microbiome composition. Bile acids can directly shape the gut-microbiome and can be modified by bacteria such as Eggerthella lenta which in turn plays a crucial role in host metab...
ORGANISM(S): Anaerostipes caccae DSM 14662 Eggerthella lenta DSM 2243 Escherichia coli str. K-12 substr. MG1655 Erysipelatoclostridium ramosum DSM 1402 
2023-02-24 | PXD035496 | Pride
Metabolomics Metaproteomics Host-gut interaction Eggerthella lenta Bile acids Gut microbiome 
UnknownAcute kidney injury after out-of-hospital cardiac arrest.
Not available
S-EPMC11102609 | biostudies-literature
UnknownMetformin may adversely affect orthostatic blood pressure recovery in patients with type 2 diabetes: substudy from the placebo-controlled Copenhagen Insulin and Metformin Therapy (CIMT) trial.
Not available
S-EPMC7520024 | biostudies-literature
UnknownMaintenance and functional regulation of immune memory to COVID-19 vaccines in tissues.
Not available
S-EPMC11634668 | biostudies-literature
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