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UnknownPublic Awareness of Dyslipidemia Among the Korean Population: A Survey Study.

Objective

We aimed to assess the level of public awareness regarding dyslipidemia and its management among the Korean population.

Methods

We conducted a web- or mobile-based survey study targeting the general population, using various recruitment methods, between July 25, 2022 and Aug...
S-EPMC10548193 | biostudies-literature
UnknownInhibition of Microglia-Derived Oxidative Stress by Ciliary Neurotrophic Factor Protects Dopamine Neurons In Vivo from MPP⁺ Neurotoxicity.
We demonstrated that capsaicin (CAP), an agonist of transient receptor potential vanilloid subtype 1 (TRPV1), inhibits microglia activation and microglia-derived oxidative stress in the substantia nigra (SN) of MPP⁺-lesioned rat. However, the detailed mechanisms how microglia-derived oxidative stres...
S-EPMC6274815 | biostudies-literature
UnknownDyslipidemia Fact Sheet in South Korea, 2022.

Backgruound

This study aimed to investigate the prevalence and status of dyslipidemia management among South Korean adults, as performed by the Korean Society of Lipid and Atherosclerosis under the name Dyslipidemia Fact Sheet 2022.

Methods

We analyzed the lipid profiles, age-standard...
S-EPMC10555536 | biostudies-literature
UnknownIn vivo AAV1 transduction with hRheb(S16H) protects hippocampal neurons by BDNF production.
Recent evidence has shown that Ras homolog enriched in brain (Rheb) is dysregulated in Alzheimer's disease (AD) brains. However, it is still unclear whether Rheb activation contributes to the survival and protection of hippocampal neurons in the adult brain. To assess the effects of active Rheb in h...
S-EPMC4351465 | biostudies-literature
UnknownPreliminary Study on Effect of Lactiplantibacillus plantarum on Osteoporosis in the Ovariectomized Rat.
Osteoporosis is a growing global health concern primarily associated with decreased estrogen in postmenopausal women. Recently, some strains of probiotics were examined for potential anti-osteoporotic effects. This study intended to evaluate the impacts of Lactiplantibacillus plantarum MGE 30...
S-EPMC10359845 | biostudies-literature
UnknownN-terminal truncated UCH-L1 prevents Parkinson's disease associated damage.
Ubiquitin C-terminal hydrolase-L1 (UCH-L1) has been proposed as one of the Parkinson's disease (PD) related genes, but the possible molecular connection between UCH-L1 and PD is not well understood. In this study, we discovered an N-terminal 11 amino acid truncated variant UCH-L1 that we called NT-U...
S-EPMC4069018 | biostudies-literature
UnknownDyslipidemia Fact Sheet in South Korea, 2022.

Objective

This study aimed to investigate the prevalence and status of dyslipidemia management among South Korean adults, as performed by the Korean Society of Lipid and Atherosclerosis under the name Dyslipidemia Fact Sheet 2022.

Methods

We analyzed the lipid profiles, age-standardiz...
S-EPMC10548191 | biostudies-literature
UnknownBlood transcriptome differentiates clinical clusters for asthma.

Background

In previous studies, several asthma phenotypes were identified using clinical and demographic parameters. Transcriptional phenotypes were mainly identified using sputum and bronchial cells.

Objective

We aimed to investigate asthma phenotypes via clustering analysis using cl...
S-EPMC10839776 | biostudies-literature
UnknownTRPV1 on astrocytes rescues nigral dopamine neurons in Parkinson's disease via CNTF.
Currently there is no neuroprotective or neurorestorative therapy for Parkinson's disease. Here we report that transient receptor potential vanilloid 1 (TRPV1) on astrocytes mediates endogenous production of ciliary neurotrophic factor (CNTF), which prevents the active degeneration of dopamine neuro...
S-EPMC4840550 | biostudies-literature
UnknownFacility-based and home-based multidomain interventions including cognitive training, exercise, diet, vascular risk management, and motivation for older adults: a randomized controlled feasibility trial.
We aimed to evaluate the feasibility of multidomain intervention (MI) tailored to the Korean context. In an outcome assessor-blinded, randomized controlled trial, participants without dementia and with one or more modifiable dementia risk factors, aged 60-79 years, were randomly assigned to the faci...
S-EPMC8266338 | biostudies-literature
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