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UnknownPreclinical evaluation of CD8+ anti-BCMA mRNA CAR T cells for treatment of multiple myeloma.
Not available
S-EPMC7785573 | biostudies-literature
TranscriptomicsRNA-seq from sorted population of CD8 T cells (50 cells per sample) of human CD8 T memory stem cells (Tscm) subsets defined by surface expression of CD122 or CXCR3
Although it is recognised that CD8+ T memory stem cells (Tscm) are heterogeneous in phenotype and function, very few studies have sought to systematically examine these characteristics, particularly in human samples, as the population as a whole is rare and antigen-specific cells even more so. For e...
ORGANISM(S): Homo sapiens 
2022-03-10 | E-MTAB-10208 | biostudies-arrayexpress
ProteomicsHigh-density CRISPRi screens reveal adaptive transcriptional gradients in cyanobacteria
Cyanobacteria are the oldest form of photosynthetic life and contribute to primary production in nearly every habitat, from permafrost to hot springs. Despite longstanding interest in the biochemical basis of environmental adaptation in these microbes, it remains poorly understood. Here we used a hi...
ORGANISM(S): Synechococcus Sp. Pcc 7002 (ncbitaxon:32049) 
2024-04-18 | MSV000094564 | MassIVE
TranscriptomicsSingle cell RNA-sequencing of PBMC derived B cells from human healthy donor
Motivation: The B-cell receptor (BCR) performs essential functions for the adaptive immune system including recognition of pathogen-derived antigens. The vast repertoire and adaptive variation of BCR sequences due to V(D)J recombination and somatic hypermutation (SHM) necessitates single-cell charac...
ORGANISM(S): Homo sapiens 
2018-06-22 | E-MTAB-6386 | biostudies-arrayexpress
UnknownProspective, Randomized, Double-Blind, Phase III Clinical Trial of Anti-T-Lymphocyte Globulin to Assess Impact on Chronic Graft-Versus-Host Disease-Free Survival in Patients Undergoing HLA-Matched Unrelated Myeloablative Hematopoietic Cell Transplantation.
Not available
S-EPMC8462523 | biostudies-literature
GenomicsNIDDK IBD Genetics Consortium Ulcerative Colitis Genome-Wide Association Study

This dataset contains data for 1,028 white, non-Hispanic, European ancestry individuals with ulcerative colitis who were included in a genome-wide association study published by Silverberg et al. (2009). These individuals were ascertained in North America and selected to have either left-sided ...

phs000345.v1.p1 | EGA
TranscriptomicsRNA-seq expression data from EB-HSPCs after HOXA7 overexpression
HOXA7 regulates FL-HSPC self-renewal in vitro and in vivo. We profiled EB-HSPCs after HOXA7 overexpression (EB-HOXA7), or with a control vector (EB-CTR), to assess the gene expression programs regulated by HOXA7. CD34+CD38-CD43+CD90+ HSPCs were infected with lentiviral FUGW vector either empty (FUG...
ORGANISM(S): Homo sapiens 
2016-05-16 | E-GEOD-76684 | biostudies-arrayexpress
TranscriptomicsRNA-seq expression data from EB-HSPC after AM580 treatment compated to DMSO-trated and FL-HSPCs
RA signalling regulated endothelial to hematopoietic transition and HSC generation. EB- or FL-derived HSPC were profiled before (d0) or after (d6) 6 days of treatment with 0.2uM AM580 on OP9, and after 6 additional days of expandion of OP9 (d12) without treatment.
ORGANISM(S): Homo sapiens 
2016-05-16 | E-GEOD-76682 | biostudies-arrayexpress
UnknownCohort profile: the WHO Child Mortality Risk Stratification Multi-Country Pooled Cohort (WHO-CMRS) to identify predictors of mortality through early childhood.
Not available
S-EPMC11605845 | biostudies-literature
UnknownA second update on mapping the human genetic architecture of COVID-19.
Not available
S-EPMC10482689 | biostudies-literature
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