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ProteomicsA small molecule targeting NMHC IIA phosphorylation exerts promising anti-tumor effects on colorectal cancer
Colorectal cancer (CRC) is one of the most lethal cancers when it progresses to the advanced/metastatic stage. Treatment options for refractory metastatic colorectal cancer (mCRC) are limited. Therefore, there is an urgent need to develop effective treatment methods for metastatic colorectal cancer....
ORGANISM(S): Homo sapiens (Human) 
2023-09-02 | PXD044543 | Pride
Refractory metastatic colorectal cancer  nmhc iia  phosphorylation  yap/akt/foxo pathway  ls-1-2 
ProteomicsPredictive Value of Proteomic Markers for Advanced Rectal Cancer with Neoadjuvant Chemoradiotherapy
Thirteen paired pre- and post-nCRT sera from rectal cancer patients were analyzed by isobaric tags for relative and absolute quantitation (iTRAQ) method. Twenty-five proteins were selected for validation by parallel reaction monitoring (PRM) in ninety-one patients.
ORGANISM(S): Homo Sapiens 
2022-03-08 | PXD032117 |
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