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TranscriptomicsGene expression profiling of Eed knockout and Ezh2 knockout small intestinal crypts [RNA-seq]
Polycomb-mediated gene repression plays an important role in adult stem cell maintenance. We knocked out (using the inducible AhCre-LoxP system) Polycomb genes Eed and Ezh2 in the intestine for 6 weeks, after which crypts - the small intestinal stem cell zone - were harvested and RNA sequenced. We f...
ORGANISM(S): Mus musculus 
2016-07-01 | E-GEOD-81576 | biostudies-arrayexpress
TranscriptomicsA mouse model of deregulation of the malt1 oncogene recapitulates the pathogenesis of human malt lymphoma [MouseSca1 dataset]
Attempts at modeling chromosomal translocations involving MALT1 gene, hallmarks of human mucosa-associated lymphoid tissue (MALT) lymphoma, have failed to reproduce the disease in mice. Here we describe a transgenic model in which MALT1 expression was targeted to mouse hematopoietic stem/progenitor ...
ORGANISM(S): Mus musculus 
2012-07-09 | E-GEOD-25636 | biostudies-arrayexpress
TranscriptomicsA mouse model of deregulation of the malt1 oncogene recapitulates the pathogenesis of human malt lymphoma [Spleen dataset]
Attempts at modeling chromosomal translocations involving MALT1 gene, hallmarks of human mucosa-associated lymphoid tissue (MALT) lymphoma, have failed to reproduce the disease in mice. Here we describe a transgenic model in which MALT1 expression was targeted to mouse hematopoietic stem/progenitor ...
ORGANISM(S): Mus musculus 
2012-07-09 | E-GEOD-25637 | biostudies-arrayexpress
TranscriptomicsA mouse model of deregulation of the malt1 oncogene recapitulates the pathogenesis of human malt lymphoma [MALT dataset]
Attempts at modeling chromosomal translocations involving MALT1 gene, hallmarks of human mucosa-associated lymphoid tissue (MALT) lymphoma, have failed to reproduce the disease in mice. Here we describe a transgenic model in which MALT1 expression was targeted to mouse hematopoietic stem/progenitor ...
ORGANISM(S): Homo sapiens 
2012-07-09 | E-GEOD-25638 | biostudies-arrayexpress
Genomicsena-DATASET-DKFZ-IBIOS-17-08-2015-09:13:01:216-19 - samples
PAR-CLIP was performed on the Argonaute-2 protein (AGO2) in four lymphoma cell lines: Namalwa Raji SU-DHL-4 SU-DHL-6
EGAD00001001468 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-16-11-2015-13:05:39:993-4 - samples
Part of WGS seq data of Maligant Lymphoma study (ICGC)
EGAD00001001673 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-16-09-2015-13:05:30:578-414 - samples
After overexpression and knockdown of both described novel miRs nmiR-1 and nmiR-2 in BL cell lines (SU-DHL4 for nmiR-1 and Raji for nmiR-2), we performed regular RNA-Seq (including Mock controls for all cell lines) to identify their direct and indirect downstream mRNA targets.
EGAD00001001612 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-06-10-2015-14:15:14:065-198 - samples
miRNA seq data of 13 cases (MMML)
EGAD00001001632 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-16-11-2015-12:46:40:494-3 - samples
Part of RNA sequencing data of Malignant Lymphoma Study (ICGC)
EGAD00001001672 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-23-09-2015-12:28:32:695-418 - samples
miRNA seq data of 43 cases out of dataset EGAD00001000650 (MMML)
EGAD00001001619 | EGA
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