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The flagellum provides essential motility in the pathogenic process of Salmonella host invasion. However, flagellin is strongly antigenic and can be recognized by TLR5, resulting in activation of the host immune system to clear the invading pathogen. The presence of flagella also disrupts the integr...
ORGANISM(S): Escherichia coli 
2022-10-12 | PXD035693 | Pride
Transition metal iron is essential for bacterial survival and growth. For pathogenic bacteria, this challenge is even more severe since human and other mammals have evolved a complicated mechanism of nutritional immunity to restrict iron availability. Preliminary research findings that iron deficien...
ORGANISM(S): Salmonella typhimurium (strain 14028s / SGSC 2262) 
2022-04-27 | PXD023378 | Pride
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