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Non-canonical microRNAs (miRNAs) are a class of short endogenous RNA molecules with the ability to control development, autophagy, apoptosis and the stress response in eukaryotes by pairing with partially complementary sites in the 3' untranslated regions (UTRs) of targeted genes. Recent studies hav...
ORGANISM(S): Bos taurus 
Extreme environmental conditions at high altitude, such as hypobaric hypoxia, low temperature, and strong UV radiation, pose a great challenge to the survival of animals. Although the mechanisms of adaptation to high-altitude environments have attracted much attention for native plateau species, the...
2024-01-16 | MTBLS6900 | MetaboLights
raw data-independent acquisition (DIA) quantitative proteomics data for Enzyme Activity-Independent NANS Stabilizes LATS2 to Drive Growth and Confer Resistance to Endocrine Therapy and CDK4/6 Inhibitors in HR+/HER2- Breast Cancer
ORGANISM(S): Homo sapiens (Human) 
2026-06-05 | PXD065351 | Pride
LC-MS data for Enzyme Activity-Independent NANS Stabilizes LATS2 to Drive Growth and Confer Resistance to Endocrine Therapy and CDK4/6 Inhibitors in HR+/HER2- Breast Cancer
ORGANISM(S): Homo sapiens (Human) 
2025-12-14 | PXD065340 | Pride
Background: Although there is an ongoing understanding of psoriasis vulgaris (PV) pathogenesis, little is known about the proteomic diversity of psoriatic lesions between moderate and severe psoriasis. Objective: To evaluate the proteomic differences between moderate and severe psoriasis and determi...
ORGANISM(S): Homo Sapiens 
2024-06-06 | PXD052886 |

Recent evidence shows elevated circulating long-chain ceramide levels predicts atherosclerotic cardiovascular disease (ASCVD) independently of cholesterol. Although targeting ceramides signaling may provide therapeutic benefits beyond the treatment of hypercholesterolemia, the underlying mechanis...

2025-04-15 | MTBLS11925 | MetaboLights
Adalimumab and secukinumab are commonly used for moderate-severe psoriasis vulgaris (PV), but distinct individual response and impaired effectiveness happen occasionally. Little is known about it. Here, we report a proteomic analysis of psoriatic lesions from patients treated with these drugs using ...
ORGANISM(S): Homo Sapiens 
2022-10-20 | PXD037579 |
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