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MetabolomicsDifferent regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using in-cell NMR spectroscopy, we d...
2021-10-06 | MTBLS1503 | MetaboLights
ProteomicsMechanistic view of NMNAT chaperoning different pathological proteins against amyloid aggregation
The cross-linking mass spectrometry raw data of NMNAT and amyloid client proteins including α-syn, K19, Aβ40, and IAPP.
ORGANISM(S): Homo Sapiens 
2022-02-11 | PXD031653 |
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