S. maltophilia was exposed to a simulated microgravity (SMG) environment in high-aspect ratio rotating-wall vessels bioreactors for 14 days, while the control group was performed in the same bioreactors under normal gravity (NG) environment. After that, combined phenotypic, genomic, transcriptomic a...
We used array CGH data from Eµ-myc lymphomas to assess significant differences in DNA copy number variation between Cluster 1 and Cluster 2 lymphomas. When Eµ-myc mice had evidence of lymphoma and/or ill appearance, they were humanely sacrificed and dissected. Lymphoma tissue was obtained and flash...
Lipids and lipid metabolism play an important role in RNA virus replication, which typically occurs on host cell endomembrane structures in the cytoplasm through mechanisms that are not yet fully identified. We conducted genome-scale CRISPR screening and identified sphingomyelin synthase 1 (SMS1; en...
Hippocampal proteins were extracted from the brain tissues of APP+SA and APP+EDB mice. The proteomics experiments and subsequent bioinformatics analysis were supported by OE Biotech Co..
We established E.coli and LPS induced ALI murine model. Then, at 24 hours, the exosome from the BALF were extracted by the Size Exclusion Chromatography (SEC) method and analyzed by quantitive mass spectrometry
This file include 9 sample: heart sample from WT mice (1, 2, 3)+heart sample from WT mice treated with DOX (4,5,6)+heart sample from HINT2 cKO mice treated with DOX (7,8,9))
Herein, we assembled a cohort composed of 254 CRC patients, including discovery cohort (N = 124) and validation cohort (N = 130), which received either chemotherapy (mainly FOLFOX therapy), chemoradiotherapy (mainly FOLFOX combined with radiotherapy), or targeted combination therapy (mainly FOLFOX c...
To explore the biological insights into squamous cell carcinoma (SCC) derived from different organs, we reported a deep proteomic analysis of 333 SCCs of 17 organs and 69 adenocarcinomas (ACs) of 7 organs. Proteomic comparison between pan-SCCs and pan-ACs identifies distinguishable pivotal pathways,...
