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TranscriptomicsGene expression signatures for primary tumor and tumor-derived exosomes
To determine the different gene signatures between primary tumor and tumor-derived exosomes, we have employed RNA-sequencing as a discovery platform to identify gene signatures of tumor-derived exosomes, taking the original tumors as a control. We subcutaneously inoculated C57BL/6 mice with Lewis lu...
ORGANISM(S): Mus musculus 
2016-08-10 | E-GEOD-80678 | biostudies-arrayexpress
TranscriptomicsGene expression signatures for murine alveolar type II lung epithelial cells after tumor bearing
To determine the influence of primary tumors on pre-metastatic lungs, we have employed whole genome microarray expression profiling as a discovery platform to identify gene signatures of alveolar type II epithelial cells (AT-II) in TLR3 deficient mice (Tlr3-/-) and wide-type (WT) littermates with tu...
ORGANISM(S): Mus musculus 
2016-08-10 | E-GEOD-76397 | biostudies-arrayexpress
ProteomicsThe association between baseline serum lipids and renal outcome in microscopic polyangiitis patients
ANCA associated vasculitis(AAV) is a systemic vasculitis of small vessels, characterzied by injury of vascular endothelial cells induced by abnormally activated neutrophils. Microscopic polyangiitis (MPA) is a member of AAV with a high risk of kidney involvement. Blood lipid disorder promotes endoth...
ORGANISM(S): Homo sapiens (Human) 
2025-01-06 | PXD045969 | Pride
Plasma 
TranscriptomicsNovel viruses naturally infecting Caenorhabditis nematodes trigger a small RNA response
C. elegans has served as a laboratory model organism due to its ease of manipulation and the availability of both forward and reverse genetics. In recent years, efforts to study host-pathogen interactions in C. elegans have increased. For example, analysis of infections by bacteria such as Pseudomon...
ORGANISM(S): Caenorhabditis elegans 
2011-01-01 | E-GEOD-21736 | biostudies-arrayexpress
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