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UnknownPersonalized medicine modality based on patient-derived xenografts from a malignant transformed GCTB harboring H3F3A G34W mutation.
Not available
S-EPMC8173097 | biostudies-literature
ProteomicsProteomic research on effect of EIF4A1 inhibition in MYC-amplified Group 3 medulloblastoma
As the most life-threatening subtype of pediatric medulloblastoma (MB), MYC-amplified Group 3 (G3) MB lacks effective and selective therapeutics. We tried to indirectly target MYC (oncogenic driver and cancer-dependent molecule) production via inhibiting translational machinery. Through multiple dat...
ORGANISM(S): Homo Sapiens 
2020-10-15 | PXD022014 |
ProteomicsNeuroprotective Effects of Desert Organic Milk Exosomes Against LPS-Induced Cognitive Impairment: Involvement of Microglial M2 Polarization and AMPK Signaling
Hippocampal neuroinflammation (HNF) is a key pathological feature in neurodegenerative disorders. Milk-derived exosomes are bioactive extracellular vesicles, yet their potential to regulate neuroinflammatory responses in the brain remains underexplored. This study aimed to characterize the superior ...
ORGANISM(S): Bos Taurus 
2025-12-11 | PXD071863 |
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