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MetabolomicsDifferential effects of Huang-Lian-Jie-Du Decoction on Alzheimer’s disease and normal rats

Introduction: Huang-Lian-Jie-Du Decoction (HLJDD), a botanical drug used in traditional medicine, has been used in the management of Alzheimer’s disease (AD). However, the mechanisms underlying its preventive effects remain inadequately understood, particularly due to the absence of metabolomic s...

2025-11-04 | MTBLS13256 | MetaboLights
UnknownBioactive Components and Potential Mechanism Prediction of Kui Jie Kang against Ulcerative Colitis via Systematic Pharmacology and UPLC-QE-MS Analysis.
Not available
S-EPMC9239780 | biostudies-literature
TranscriptomicsNext Generation Sequencing Facilitates Quantitative Analysis of Wild Type and rea1 mutant Transcriptomes
Analysis of gene expression level. The hypothesis tested in the present study was that rea1 mutant influence the expression of translation and nucleosome assembly associated genes. Results provide important information of the gene expression level regulation of ribosome proteins, elongation factors...
ORGANISM(S): Zea mays 
2015-04-25 | E-GEOD-67080 | biostudies-arrayexpress
TranscriptomicsNext Generation Sequencing Facilitates Quantitative Analysis of Wild Type and rea1 mutant total and polysome-bound Transcriptomes
Analysis of gene expression level. The hypothesis tested in the present study was that rea1 mutant influence the translation level of translation and nucleosome assembly associated genes. Results provide important information of the gene translation level regulation of ribosome proteins, elongation...
ORGANISM(S): Zea mays 
2015-04-25 | E-GEOD-67083 | biostudies-arrayexpress
MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
MetabolomicsGut microbiota-driven regulation of queen bee ovarian metabolism

With the global prevalence of Varroa mites, more and more beekeepers resort to confining the queen bee in a queen cage to control mite infestation or to breed superior and robust queen bees. However, the impact of such practices on the queen bee remains largely unknown. Therefore, we sub...

2023-09-11 | MTBLS7576 | MetaboLights
MetabolomicsMetabolomics reveals molecular signatures for psoriasis biomarkers and drug targets discovery
Psoriasis is a chronic skin disease that affects multiple systems and can be influenced by immunological, environmental, and genetic factors. The discovery of plasma biomarkers of psoriasis and the regulation of metabolic pathways helps us understand psoriasis and may assist clinicians in the diagno...
2024-09-26 | MTBLS5185 | MetaboLights
Proteomics5×FAD mouse hippocampus ECM proteomics
ECM proteins were up-regulated mostly in both SDS-soluble and SDS-insoluble group of 5×FAD model
ORGANISM(S): Mus musculus (Mouse) 
2026-09-14 | PXD072193 | Pride
Mouse Hippocampus Alzheimer's disease 
ProteomicsProteomics of human hippocampus
ECM proteins were up-regulated mostly in AD patients
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD072140 | Pride
Brain Hippocampus Alzheimer's disease Human 
UnknownAnti-lung cancer therapy using nano-assembly particles of traditional Chinese Medicine formula.
Not available
S-EPMC12661425 | biostudies-literature
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