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TranscriptomicsPerinatal malnutrition in male mice influences gene expression in the next generation offspring: Potential role of epigenetics.
Perinatal nutritional imbalances may have long-lasting consequences on health and disease, increasing risk of obesity, insulin resistance, type 2 diabetes or cardiovascular disease. This idea has been conceptualized in the Developmental Origins of Health and Disease Hypothesis (DOHaD). In additi...
ORGANISM(S): Mus musculus 
2015-02-01 | E-GEOD-55304 | biostudies-arrayexpress
MetabolomicsUntargeted metabolomics identifies a plasma sphingolipid-related signature associated with lifestyle intervention in prepubertal children with obesity

OBJECTIVE: Childhood obesity is a strong risk factor for adult obesity and metabolic diseases, including type 2 diabetes and cardiovascular disease. Early lifestyle intervention in children with obesity reduces future disease risk. The objective of this study is to identify metab...

2018-02-09 | MTBLS423 | MetaboLights
UnknownBenchmarking of methods to analyse data derived from GBS-MeDIP.
Not available
S-EPMC12829230 | biostudies-literature
UnknownGenetic polymorphisms lead to major, locus-specific, variation in piRNA production in mouse.
Not available
S-EPMC12264111 | biostudies-literature
UnknownExpression of the splicing factor gene SFRS10 is reduced in human obesity and contributes to enhanced lipogenesis.
Not available
S-EPMC3167228 | biostudies-literature
UnknownTransgenerational inheritance of hepatic steatosis in mice: sperm methylome is largely reprogrammed and inherited but does not globally influence liver transcriptome.
Not available
S-EPMC11879089 | biostudies-literature
UnknownResponse to Brosch et al.
Not available
S-EPMC4425348 | biostudies-literature
UnknownNeonatal overfeeding during lactation rapidly and permanently misaligns the hepatic circadian rhythm and programmes adult NAFLD.
Not available
S-EPMC7851182 | biostudies-literature
UnknownIncreasing breast milk betaine modulates Akkermansia abundance in mammalian neonates and improves long-term metabolic health.
Not available
S-EPMC8823629 | biostudies-literature
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