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TranscriptomicsGSTP1 expression predicts poor pathological complete response to neoadjuvant chemotherapy in ER-negative breast cancer
The purpose of the present study was to investigate the association of glutathione S-transferase P1 (GSTP1) expression with resistance to neoadjuvant paclitaxel followed by 5-fluorouracil/epirubicin/cyclophosphamide (P-FEC) in human breast cancers. The relationship of GSTP1 expression and GSTP1 prom...
ORGANISM(S): Homo sapiens 
2012-03-20 | E-GEOD-32646 | biostudies-arrayexpress
TranscriptomicsMolecular signaling distinguishes early from late recurrences in ER positive breast cancer
Unlike many other cancers, estrogen receptor-alpha (ER+) breast cancers are associated with cumulative risks of recurrence and death that persist for decades. We show that molecular differences between breast cancers that recur at distant sites early (² 3 years) or late (³ 5 years) support a robust ...
ORGANISM(S): Homo sapiens 
2015-04-15 | E-GEOD-46222 | biostudies-arrayexpress
GenomicsGenome-wide analysis of transcription factor E2F1 mutant proteins reveals that N- and C-terminal protein interaction domains do not participate in targeting E2F1 to the human genome.
Previous studies of E2F family members have suggested that protein-protein interactions may be the mechanism by which E2Fs are recruited to specific genomic regions. We have addressed this hypothesis on a genome-wide scale using ChIP-seq analysis of MCF7 cell lines that express tagged wildtype and m...
ORGANISM(S): Homo sapiens 
2011-04-04 | E-GEOD-28286 | biostudies-arrayexpress
UnknownThe ER Chaperones BiP and Grp94 Regulate the Formation of Insulin-Like Growth Factor 2 (IGF2) Oligomers.
Not available
S-EPMC8169611 | biostudies-literature
UnknownYeast lunapark regulates the formation of trans-Sey1p complexes for homotypic ER membrane fusion.
Not available
S-EPMC10679814 | biostudies-literature
UnknownThe E3 ligase Hrd1 stabilizes Tregs by antagonizing inflammatory cytokine-induced ER stress response.
Not available
S-EPMC6483511 | biostudies-literature
UnknownInfection by and genotype characteristics of Enterocytozoon bieneusi in HIV/AIDS patients from Guangxi Zhuang autonomous region, China.
Not available
S-EPMC5640944 | biostudies-literature
UnknownAn RXLR effector disrupts vesicle trafficking at ER-Golgi interface for Phytophthora capsici pathogenicity.
Not available
S-EPMC11683230 | biostudies-literature
ProteomicsEstrogen Receptor Mutant Coregulator
Biotinylated 4xERE-containing DNA immobilized on streptavidin beads used to pulldown proteins recruited by unliganded WT ER-alpha versus Y537S, D538G, or ESR1-YAP1 fusion proteins from HeLa S3 human cell nuclear extracts.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-02-08 | MSV000080536 | MassIVE
UnknownSustained mTORC1 activity during palbociclib-induced growth arrest triggers senescence in ER+ breast cancer cells.
Not available
S-EPMC7849761 | biostudies-literature
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