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TranscriptomicsCooperativity and Equilibrium with FOXA1 Define Androgen Receptor Transcriptional Program
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-06-02 | E-GEOD-55007 | biostudies-arrayexpress
TranscriptomicsAndrogen receptor-independent function of FoxA1 in prostate cancer metastasis
FoxA1 has been shown critical for prostate development and prostate-specific gene expression regulation. In addition to its well-established role as an AR pioneering factor,several studies have recently revealed significant AR binding events in prostate cancer cells with FoxA1 knockdown. Furthermore...
ORGANISM(S): Homo sapiens 
2013-04-05 | E-GEOD-37314 | biostudies-arrayexpress
TranscriptomicsCooperativity and Equilibrium with FOXA1 Define Androgen Receptor Transcriptional Program [array]
Previous studies have shown that FOXA1 defines prostatic AR binding events, the underlying mechanisms of which, however, are incompletely understood. To test whether ectopic AR and FOXA1 can activate AR target genes, we performed adenoviral of LacZ, AR, FOXA1 or AR+FOXA1 proteins in DU145 cells, fo...
ORGANISM(S): Homo sapiens 
2014-06-02 | E-GEOD-54991 | biostudies-arrayexpress
GenomicsFoxA1 inhibits androgen receptor expression and suppresses prostate cancer metastasis [LNCaP, ChIP-seq]
FoxA1 has been shown critical for prostate development and prostate-specific gene expression regulation. In addition to its well-established role as an AR pioneering factor,several studies have recently revealed significant AR binding events in prostate cancer cells with FoxA1 knockdown. Furthermore...
ORGANISM(S): Homo sapiens 
2014-06-02 | E-GEOD-37345 | biostudies-arrayexpress
GenomicsFoxA1 inhibits androgen receptor expression and suppresses prostate cancer metastasis [DU145, ChIP-seq]
FoxA1 has been shown critical for prostate development and prostate-specific gene expression regulation. In addition to its well-established role as an AR pioneering factor,several studies have recently revealed significant AR binding events in prostate cancer cells with FoxA1 knockdown. Furthermore...
ORGANISM(S): Homo sapiens 
2014-06-02 | E-GEOD-47987 | biostudies-arrayexpress
GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

phs000361.v1.p1 | EGA
ProteomicsUsing patient-derived organoids to predict locally advanced or metastatic lung cancer tumor response: a real-world study
Using patient derived lung cancer organoids to predict clinical response and find theraputic mechanisms
ORGANISM(S): Homo Sapiens 
2022-09-26 | PXD037076 |
UnknownNew insights into the genetic etiology of Alzheimer's disease and related dementias.
Not available
S-EPMC9005347 | biostudies-literature
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