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TranscriptomicsExpression data from embryonic stem cells differentiation
Pluripotency-associated transcription factor Foxd3 is required for maintaining pluripotent cells. However, the molecular mechanisms underlying its function are largely unknown. Here, we report that Foxd3 maintains the ESC identity through counteracting differentiation induction of Calcienurin-NFAT s...
ORGANISM(S): Mus musculus 
2014-08-18 | E-GEOD-58960 | biostudies-arrayexpress
UnknownProtective Effects of Dexrazoxane against Doxorubicin-Induced Cardiotoxicity: A Metabolomic Study.
Not available
S-EPMC5224977 | biostudies-literature
UnknownA Phase II Study of Atezolizumab, Pertuzumab, and High-Dose Trastuzumab for Central Nervous System Metastases in Patients with HER2-Positive Breast Cancer.
Not available
S-EPMC11528201 | biostudies-literature
ModelsSaucerman2006_PKA
The model reproduces Fig 2B of the paper. Model successfully tested on MathSBML To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain...
2024-09-02 | BIOMD0000000165 | BioModels
TranscriptomicsGenome-wide analysis of gene expression regulated by calcineurin-NFAT signaling in mouse embryonic stem cells
Self-renewal and pluripotency are hallmarks of embryonic stem cells (ESCs). However, signaling pathways triggering their transition from self-renewal to differentiation are not well defined. Here, we report that the calcineurin-NFAT signaling pathway is both necessary and sufficient to switch ESCs f...
ORGANISM(S): Mus musculus 
2011-01-01 | E-GEOD-21378 | biostudies-arrayexpress
ProteomicsAn improved protein extraction method
three protein extraction methods were used for cotton leaves protein extraction, and LC-MS/MS analyses of total proteins obtained from cotton leaves.
ORGANISM(S): Gossypium Hirsutum 
2019-01-28 | PXD012517 |
ProteomicsVitamin D enhances the therapeutic effect of TNF-α antibody by lipid metabolism in overweight IBD
The colonic mucosal proteins from HFD and HFD+PAL treated mice were lysed using RIPA buffer, and protein concentration was quantified by BCA assay.
ORGANISM(S): Homo Sapiens 
PXD056116 |
GenomicsExome chip analysis file
This data set includes the following summary level data file used for the exome chip analysis: exome_chip.sv.assoc.txt: results from single variant association analysis in exome chip
EGAD00010001187 | EGA
Genomicsena-DATASET-GoT2D/T2D-GENES-09-07-2016-02:03:47:226-1135 - samples
The GoT2D study includes ~2800 samples, half T2D cases and half T2D controls, of Northern European ancestry sequenced over 3 three technologies: deep whole exome sequencing, low-pass (4x) whole genome sequencing, and OMNI 2.5M genotyping. Samples were ascertained to be phenotypically "extreme" (e.g....
EGAD00001002247 | EGA
GenomicsGoT2D: Genetics of Type 2 Diabetes, a study of the the genetic architecture of type 2 diabetes using low pass whole genome sequencing and high density SNP genotyping in 2,657 individuals.
The Genetics of Type 2 Diabetes Consortium (GoT2D) is a collaboration between the University of Michigan, the Broad Institute and the Wellcome Trust Centre for Human Genetics. The overall aim is to extend upon recent efforts, such as genome-wide association studies (GWAS) and large scale meta-analys...
EGAS00001001459 | EGA
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