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MetabolomicsLow chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
Dysregulated extravillous trophoblast invasion and proliferation are known to increase the risk of recurrent spontaneous abortion (RSA); however, the underlying mechanism remains unclear. Herein, in our retrospective observational case-control study we show that villous samples from RSA patients, co...
2021-10-06 | MTBLS2148 | MetaboLights
UnknownProbing CP symmetry and weak phases with entangled double-strange baryons.
Though immensely successful, the standard model of particle physics does not offer any explanation as to why our Universe contains so much more matter than antimatter. A key to a dynamically generated matter-antimatter asymmetry is the existence of processes that violate the combined charge conjugat...
S-EPMC9159954 | biostudies-literature
UnknownExtracting the femtometer structure of strange baryons using the vacuum polarization effect.
One of the fundamental goals of particle physics is to gain a microscopic understanding of the strong interaction. Electromagnetic form factors quantify the structure of hadrons in terms of charge and magnetization distributions. While the nucleon structure has been investigated extensively, data on...
S-EPMC11470094 | biostudies-literature
UnknownGlobal survival trends for brain tumors, by histology: analysis of individual records for 556,237 adults diagnosed in 59 countries during 2000-2014 (CONCORD-3).

Background

Survival is a key metric of the effectiveness of a health system in managing cancer. We set out to provide a comprehensive examination of worldwide variation and trends in survival from brain tumors in adults, by histology.

Methods

We analyzed individual data for adults (15...
S-EPMC10013649 | biostudies-literature
UnknownGlobal survival trends for brain tumors, by histology: Analysis of individual records for 67,776 children diagnosed in 61 countries during 2000-2014 (CONCORD-3).

Introduction

Tumors of the central nervous system are among the leading causes of cancer-related death in children. Population-based cancer survival reflects the overall effectiveness of a health care system in managing cancer. Inequity in access to care world-wide may result in survival dis...
S-EPMC10013647 | biostudies-literature
UnknownThe histology of brain tumors for 67 331 children and 671 085 adults diagnosed in 60 countries during 2000-2014: a global, population-based study (CONCORD-3).

Background

Global variations in survival for brain tumors are very wide when all histological types are considered together. Appraisal of international differences should be informed by the distribution of histology, but little is known beyond Europe and North America.

Methods

The sou...
S-EPMC8485444 | biostudies-literature
UnknownA benchmark of expert-level academic questions to assess AI capabilities.
Benchmarks are important tools for tracking the rapid advancements in large language model (LLM) capabilities. However, benchmarks are not keeping pace in difficulty: LLMs now achieve more than 90% accuracy on popular benchmarks such as Measuring Massive Multitask Language Understanding1,...
S-EPMC12851929 | biostudies-literature
UnknownGlobal surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries.
BACKGROUND:In 2015, the second cycle of the CONCORD programme established global surveillance of cancer survival as a metric of the effectiveness of health systems and to inform global policy on cancer control. CONCORD-3 updates the worldwide surveillance of cancer survival to 2014. METHODS:CONCORD-...
S-EPMC5879496 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
UnknownObservation of quantum entanglement with top quarks at the ATLAS detector.
Entanglement is a key feature of quantum mechanics1-3, with applications in fields such as metrology, cryptography, quantum information and quantum computation4-8. It has been observed in a wide variety of systems and length scales, ranging from the microscopic9-13 t...
S-EPMC11410654 | biostudies-literature
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