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ProteomicsProteomic analysis of different developmental stages of Cystoisospora suis (Apicomplexa: Coccidia) in vitro
The apicomplexan parasite Cystoisospora suis has global significance as an enteropathogen of suckling piglets. Its intricate life cycle entails a transition from an asexual phase to sexual development, ultimately leading to the formation of transmissible oocysts. To advance our understanding of the ...
ORGANISM(S): Cystoisospora suis 
2023-10-13 | PXD045050 | Pride
Swine  apicomplexa  sexual development  proteome  metabolism  oocyst  gametes Isospora suis  coccidia 
ProteomicsAn Analysis of Toxoplasma gondii Extracellular Vesicles.
Toxoplasma gondii, the causative agent of toxoplasmosis, infects roughly one-third of the global population, highlighting its remarkable adaptability and pathogenicity across a wide range of warm-blooded animals. A key aspect of T. gondii’s ability to interact with its hosts involves the secretion o...
ORGANISM(S): Toxoplasma gondii RH 
2025-03-19 | PXD055601 | Pride
Toxoplasma gondii  exovesicles  evs 
TranscriptomicsDifferentially activated CD8 T cells in liver and gut
NaM-CM-/ve, liver- and gut-activated CD8 OT-I T cells show differential migration behaviour. To analyze which genes could be responsible for different migration patterns, naM-CM-/ve, liver-activated and gut-activated CD8 T cells were isolated and compared for their gene expression profile. Gene expr...
ORGANISM(S): Mus musculus 
2014-02-25 | E-GEOD-39449 | biostudies-arrayexpress
TranscriptomicsRsk2 controls synovial fibroblast hyperplasia and the course of arthritis.
To understand differences in the pathogenesis of synovial hyperplasia during TNF-induced arthritis, we compared the global gene expression of hTNFtg and hTNFtg;Rsk2-/y primary synovial fibroblasts. Murine fibroblast-like synoviocytes (FLS) were isolated from the hind paws of hTNFtg and hTNFtg;Rsk2-/...
ORGANISM(S): Mus musculus 
2014-12-04 | E-GEOD-52992 | biostudies-arrayexpress
TranscriptomicsGene expression of resting memory, resting naive and in vitro activated memory CD8+CD127+ T cells from spleen and bone marrow (BM)
To understand differences between resting and activated memory CD8+ T cells, we compared the global gene expression of ex vivo isolated naive and spleen and BM memory cells to in vitro activated spleen and BM memory cells. Single cell suspension from the spleen and bones of aged C57BL/6 mice were pr...
ORGANISM(S): Mus musculus 
2015-02-05 | E-GEOD-62691 | biostudies-arrayexpress
TranscriptomicsHuman memory T cells of the bone marrow are resting and maintain long-lasting memory
To compare human memory CD4+ T cell subsets in peripheral blood (PB) and bone marrow (BM) of healthy individuals at transcriptional level, we analyzed the global gene expression of ex vivo PB CD69- as well as BM CD69- and CD69+ memory CD4+ T cells from 4 paired PB and BM samples. The gene expression...
ORGANISM(S): Homo sapiens 
2014-06-17 | E-GEOD-50677 | biostudies-arrayexpress
TranscriptomicsGene expression of murine B cells activated via TLR4 or TLR4 + CD40: Group1 naM-CM-/ve B cells, Group2 LPS activated B cells 24h, Group3 LPS + anti-CD40 activated B cells 24h, Group4 LPS activated B cells 72h, and Group5 LPS + anti-CD40 activated B cells 72h.
Murine B cells can be activated via the surface receptors TLR4 and CD40. For a global assessment of differences in gene expression between these two different modes of B cell activation a genome wide transcriptome analysis was performed. In order to dissect different gene expression profiles of B ce...
ORGANISM(S): Mus musculus 
2014-02-24 | E-GEOD-35998 | biostudies-arrayexpress
UnknownMacrophage-induced enteric neurodegeneration leads to motility impairment during gut inflammation
Not available
S-SCDT-10_1038-S44321-024-00189-W | biostudies-other
TranscriptomicsRole of Blimp-1 in programing Th effector cells into IL-10 producers
Gene expression profiling on IL-10-secreting and non-secreting murine Th1 cells, stimulated in the presence or absence of the Notch ligand Delta-like 4 (Dll4), was performed to identify transcription factors co-expressed with IL-10. Primary naM-CM-/ve T helper cells were isolated from lymph nodes an...
ORGANISM(S): Mus musculus 
2014-05-08 | E-GEOD-57417 | biostudies-arrayexpress
TranscriptomicsThe anti-inflammatory nature of HDL in macrophages is mediated by ATF3
Elevated plasma levels of High Density Lipoprotein (HDL) are associated with decreased risk of cardiovascular disease (CVD). The protective role of HDL in atherosclerosis has been attributed primarily to its ability to remove excess cholesterol from lipid-laden macrophages (foam cells) within the ar...
ORGANISM(S): Mus musculus 
2013-12-08 | E-GEOD-44034 | biostudies-arrayexpress
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