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TranscriptomicsPemetrexed alters inflammatory profile in EA.hy 926 cells grown under low-folate conditions.
Pemetrexed is an antifolate drug used in the treatment of lung cancer. EA.hy 926 cells grown under low (Lo) and normal (Hi) folate conditions were treated with PMX. Microarray analysis was used to examine changes in gene expression due to PMX treatment. Hi and Lo cells were grown to confluence and m...
ORGANISM(S): Homo sapiens 
2012-10-03 | E-GEOD-31986 | biostudies-arrayexpress
TranscriptomicsMethotrexate activates aspects of inflammation in EA.hy 926 cells
Methotrexate (MTX) is an anti-folate drug used to treat inflammatory diseases such as rheumatoid arthritis. The changes induced by MTX were profiled within EA.hy 926 cells grown in normal (Hi) and low (Lo) folate. Several inflammatory genes were up regulated and several mitosis related genes were do...
ORGANISM(S): Homo sapiens 
2012-09-30 | E-GEOD-32008 | biostudies-arrayexpress
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