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This model is decribed in the article: Dilution and titration of cell-cycle regulators may control cell size in budding yeast Frank S. Heldt, Reece Lunstone, John J. Tyson, Bela Novak PLoS Comput Biol, October 2018, 14(10), e1006548, doi: 10.1371/journal.pcbi.1006548 Abstract: The size of a cell se...
2024-09-02 | BIOMD0000000856 | BioModels
This model is decribed in the article: Dilution and titration of cell-cycle regulators may control cell size in budding yeast Frank S. Heldt, Reece Lunstone, John J. Tyson, Bela Novak PLoS Comput Biol, October 2018, 14(10), e1006548, doi: 10.1371/journal.pcbi.1006548 Abstract: The size of a cell se...
2019-01-09 | MODEL1803220002 | BioModels
This model is described in the article: A single light-responsive sizer can control multiple-fission cycles in Chlamydomonas Frank S. Heldt, John J. Tyson, Frederick R. Cross, Bela Novak Abstract: Most eukaryotic cells execute binary division after each mass doubling, in order to maintain size home...
2020-01-21 | MODEL1904020001 | BioModels
Ovarian cancer is the fifth leading cause of cancer death for women in the U.S. and the seventh most fatal worldwide. Although ovarian cancer is notable for its initial sensitivity to platinum-based therapies, the vast majority of women eventually recurs and succumbs to increasingly platinum-resista...
ORGANISM(S): Homo sapiens 
Changes in the transcriptome of Isc1p deficient mutants. The inositolphosphosphingolipid phospholipase C (Isc1p) of Saccharomyces cerevisiae belongs to the family of neutral sphingomyelinases that generates the bioactive sphingolipid ceramide. In this work the role of Isc1p in oxidative stress resis...
ORGANISM(S): Saccharomyces cerevisiae 
Sir2 is an NAD+-dependent histone deacetylase, and is the founding member of a large, phylogentically conserved, family of such deacetylases called the Sirtuins. The budding yeast, Saccharomyces cerevisiae, harbors 4 paralogs of Sir2, known as Hst1, Hst2, Hst3, and Hst4. Reducing the intracellular N...
ORGANISM(S): Saccharomyces cerevisiae 
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