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UnknownInteractive enhancer hubs (iHUBs) mediate transcriptional reprogramming and adaptive resistance in pancreatic cancer.
Not available
S-EPMC10402638 | biostudies-literature
UnknownHistone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4- and MYC-dependent manner.
Not available
S-EPMC5499659 | biostudies-literature
UnknownIdentification of a ΔNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma.
Not available
S-EPMC10542885 | biostudies-literature
ProteomicsOrgan protection by caloric restriction depends on activation of the de novo NAD+ synthesis pathway
Therapeutic strategies to treat acute kidney injury (AKI) are lacking. Preconditioning by hypoxia (HP) and caloric restriction (CR) is highly protective in rodent AKI models. The underlying molecular mechanisms are unknown. A comparative transcriptome analysis after HP and CR identified Kynureninase...
ORGANISM(S): Mus musculus (Mouse) 
2023-02-13 | PXD038328 | Pride
Kynu Hypoxia Caloric restriction Acute kidney injury Kynureninase Nad+ 
UnknownCHD1 loss negatively influences metastasis-free survival in R0-resected prostate cancer patients and promotes spontaneous metastasis in vivo.
Not available
S-EPMC8761572 | biostudies-literature
UnknownEmergence of new norovirus variants on spring cruise ships and prediction of winter epidemics.
Not available
S-EPMC2600213 | biostudies-literature
TranscriptomicsTranscription profiling of C. elegans daf-19(+) and daf-19(-) mutants
By screening for genes possessing canonical X-box sequences in promoters of three Caenorhabditis species, namely C. elegans, C. briggsae and C. remanei, we identified 93 genes (including known X-box regulated genes) that encode putative components of ciliated neurons in C. elegans and are subject to...
ORGANISM(S): Caenorhabditis elegans 
2008-06-14 | E-GEOD-6563 | biostudies-arrayexpress
UnknownProtocol for a multicentre randomised controlled trial of the Pharmacy Homeless Outreach Engagement Non-medical and Independent Prescriber (PHOENIx) intervention for people facing severe and multiple disadvantages.
Not available
S-EPMC12645644 | biostudies-literature
UnknownConnecting real-world digital mobility assessment to clinical outcomes for regulatory and clinical endorsement-the Mobilise-D study protocol.
Not available
S-EPMC9536536 | biostudies-literature
UnknownThe genetic determinants of recurrent somatic mutations in 43,693 blood genomes.
Not available
S-EPMC10132750 | biostudies-literature
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