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MetabolomicsAntiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19

BACKGROUND: There is a critical need for rapid viral infection diagnostics to enable prompt case identification in pandemic settings and support targeted antimicrobial prescribing.

METHODS: Using untargeted high-resolution liquid chromatography coupled with...

2022-02-10 | MTBLS718 | MetaboLights
GenomicsProgram specificity for Ptf1a in PancreasM-BM- versusM-BM- Neural Tube DevelopmentM-BM- correlates with distinctM-BM- collaborating cofactors and chromatin accessibility
Ptf1a is a lineage-specific basic-helix-loop-helix transcription factor critical in the development of both the pancreas and nervous system. How one transcription factor controls diverse programs of gene expression is a fundamental question in developmental biology. To uncover molecular strategies f...
ORGANISM(S): Mus musculus 
2013-08-15 | E-GEOD-47459 | biostudies-arrayexpress
UnknownComparison of Whole-Genome Sequencing Methods for Analysis of Three Methicillin-Resistant Staphylococcus aureus Outbreaks.
Not available
S-EPMC5442552 | biostudies-literature
Genomicscis-eQTL mapping of human pancreatic islets
The intersection of genome-wide association analyses with physiological and functional data indicates that variants regulating islet gene transcription influence type 2 diabetes predisposition and glucose homeostasis. However, the specific genes through which these regulatory variants act remain po...
EGAS00001001265 | EGA
Genomicsena-DATASET-OCDEM-04-09-2015-16:46:25:090-47 - samples
The intersection of genome-wide association analyses with physiological and functional data indicates that variants regulating islet gene transcription influence type 2 diabetes (T2D) predisposition and glucose homeostasis. However, the specific genes through which these regulatory variants act rema...
EGAD00001001601 | EGA
UnknownMapping the planet's critical areas for biodiversity and nature's contributions to people.
Not available
S-EPMC10781687 | biostudies-literature
GenomicsOxford Human Islet Data Access Committee
Data Access Committee EGAC00001000335
EGAC00001000335 | EGA
TranscriptomicsDifferential expression between Sh2b3 knockout and wild type mice
To validate the predicted Sh2b3 derived gene regulatory subnetwork using integrative network approach in human population study, we examined the gene expression levels of whole blood in WT (wild-type) and Sh2b3-/- mice by RNA sequencing, and identified the differentially expressed genes. RNA sequen...
ORGANISM(S): Mus musculus 
2015-06-17 | E-GEOD-65348 | biostudies-arrayexpress
UnknownImpact of neuraminidase inhibitors on influenza A(H1N1)pdm09-related pneumonia: an individual participant data meta-analysis.
Not available
S-EPMC4814862 | biostudies-literature
UnknownLong-term safety and efficacy of atazanavir-based therapy in HIV-infected infants, children and adolescents: the Pediatric AIDS Clinical Trials Group Protocol 1020A.
Not available
S-EPMC4355059 | biostudies-literature
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