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TranscriptomicsPrimary Sjogren's syndrome study
The objective of the study was to identify gene expression signatures in minor salivary glands (MSGs) from patients with primary Sjogren's syndrome (SS). METHODS: A 16K complementary DNA microarray was used to generate gene expression profiles in MSGs obtained from 10 patients with primary SS and 10...
ORGANISM(S): Homo sapiens 
2013-11-14 | E-MTAB-2073 | biostudies-arrayexpress
TranscriptomicsCharacterization of early stages of human B cell development by gene expression profiling
We have characterized several stages of normal human B cell development in adult bone marrow by gene expression profiling of hemopoietic stem cells, early B (E-B), pro-B, pre-B, and immature B cells, using RNA amplification and Lymphochip cDNA microarrays (n = 6). Hierarchical clustering of 758 diff...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-14714 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human acute myeloid leukemia cells before and early after the start of conventional genotoxic chemotherapy
The molecular changes in vivo in acute myeloid leukemia cells early after start of conventional genotoxic chemotherapy are incompletely understood, and it is not known if early molecular modulations reflect clinical response. The gene expression was examined by whole genome 44k oligo microarrays in ...
ORGANISM(S): Homo sapiens 
2009-02-04 | E-TABM-632 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of human prostate cell lines indicates an H3K4me3/H3K27me3 epigenetic signature of prostate carcinogenesis
This work offers a dynamic picture of epigenetic switches in carcinogenesis and contributes to an overall understanding of coordinated regulation of gene expression in cancer. Our data indicate an H3K4me3/H3K27me3 epigenetic signature of prostate carcinogenesis.
ORGANISM(S): Homo sapiens 
2009-02-12 | E-TABM-635 | biostudies-arrayexpress
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