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ProteomicsNext-generation Serology by Mass Spectrometry:Readout of the SARS-CoV-2 Antibody Repertoire
Methods of antibody detection are used to assess exposure or immunity to a pathogen. Here, we present Ig-MS, a novel serological readout that captures the immunoglobulin (Ig) repertoire at molecular resolution, including entire variable regions in Ig light and heavy chains. Ig-MS uses new advances i...
ORGANISM(S): Homo Sapiens 
2022-09-24 | PXD028627 | panorama
UnknownProphylactic rituximab after allogeneic transplantation decreases B-cell alloimmunity with low chronic GVHD incidence.
Not available
S-EPMC3383022 | biostudies-literature
TranscriptomicsGene expression profiles of null Pacman/Xrn1 mutant Drosophila L3 wing imaginal discs
Two pcm null alleles (pcm14 and pcm15) were sequenced alongside respective wild-type controls (wild-type 1 and wild-type 2). Each genotype was replicated 3 times. Read depth was 12-17 million reads per replicate. Total RNA was prepared from Drosophila L3 larval wing imaginal discs.
ORGANISM(S): Drosophila melanogaster 
2016-07-03 | E-MTAB-3789 | biostudies-arrayexpress
TranscriptomicsThe let-7-Imp axis regulates aging of the Drosophila testis stem cell niche.
Adult stem cells support tissue homeostasis and repair throughout the life of an individual. However, numerous intrinsic and extrinsic changes occur with age that result in altered stem cell behavior and reduced tissue maintenance and regeneration. In the Drosophila testis, stem cells surround and c...
ORGANISM(S): Drosophila melanogaster 
2012-05-31 | E-GEOD-37041 | biostudies-arrayexpress
UnknownCan Marginal Rates of Substitution Be Inferred From Happiness Data? Evidence from Residency Choices.
Not available
S-EPMC4231441 | biostudies-literature
TranscriptomicsRadical prostatectomy specimens with and without TMPRSS2:ERG fusion from 139 patients with prostate in a Toronto cohort
Prostate tumors with the gene fusion TMPRSS2:ERG have been reported to have a significantly higher risk of recurrence compared with tumors lacking the fusion. Tumors from 139 patients who underwent radical prostatectomy were analyzed for the expression of 502 cancer-related genes to identify genes d...
ORGANISM(S): Homo sapiens 
2009-10-22 | E-GEOD-18655 | biostudies-arrayexpress
GenomicsNucleosome map of the IMR90 fibroblast cell line
We produced a map of nucleosome positions in IMR90 by sequencing the ends of MNase-digested chromatin fragments. IMR90 cells were grown in culture, about 1E6 cells were isolated and digested using micrococcal nuclease (MNase). Mononucleosomes were gel-selected and fragment ends were sequenced using ...
ORGANISM(S): Homo sapiens 
2011-04-01 | E-GEOD-21823 | biostudies-arrayexpress
ProteomicsProteomics of vascularized cardiac organoids
Crosstalk between cardiac cells is critical during heart development but its role in organ maturation is still largely uncharacterised. Here, we show that endothelial cells increas the force of contraction and enhance the expression of mature sarcomeric proteins and extracellular matrix (ECM) compon...
ORGANISM(S): Homo sapiens (Human) 
2025-11-06 | PXD019266 | Pride
Cardioac organoids Endothelial cells 
GenomicsH2A.Z Mapping During G0/G1 and Mitosis
We report genome wide mapping of the histone variant H2A.Z during G0/G1 and mitosis in T24 bladder cancer cells. The results show that the broad enrichment pattern of H2A.Z near transcription start sites of active genes is maintained during mitosis. Furthermore, using H2A.Z localization to visuali...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-19568 | biostudies-arrayexpress
TranscriptomicsThe effect of Dis3 knockdown on miRNA expression in Drosophila wing imaginal discs.
We investigated the effect on miRNA expression in Drosophila melanogaster wing imaginal discs following the knockdown of the 3'-5' exoribonuclease Dis3.
ORGANISM(S): Drosophila melanogaster 
2015-06-01 | E-MTAB-3569 | biostudies-arrayexpress
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