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TranscriptomicsCerebellar gene expression profiles of mouse models for Rett Syndrome reveal MeCP2 targets
Background MeCP2, methyl-CpG-binding protein 2, binds to methylated cytosines at CpG dinucleotides, as well as to unmethylated DNA, and affects chromatin condensation. MECP2 mutations in females lead to Rett syndrome, a neurological disorder characterized by developmental stagnation and regression,...
ORGANISM(S): Mus musculus 
2007-08-15 | E-GEOD-8774 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of cerebellum from Mecp2 mutant mice to identify pathways mis-regulated by MeCP2 deficiency in Rett Syndrome
Background MeCP2, methyl-CpG-binding protein 2, binds to methylated cytosines at CpG dinucleotides, as well as to unmethylated DNA, and affects chromatin condensation. MECP2 mutations in females lead to Rett syndrome, a neurological disorder characterized by developmental stagnation and regression,...
ORGANISM(S): Mus musculus 
2007-07-17 | E-SMDB-4087 | biostudies-arrayexpress
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