Sort   by:  
 Page size 
TranscriptomicsGene expression of T47D-MTVL human breast cancer cells upon H1X knock-down
Gene expression of T47D-MTVL human breast cancer cells expressing Dox-inducible shRNAs against histone H1X Stable breast cancer-derived cell lines expressing an shRNA against the histone H1X isoforms in response to doxycycline (Dox) were grown for six days in the presence or absence of Dox, and seru...
ORGANISM(S): Homo sapiens 
2015-04-02 | E-GEOD-62766 | biostudies-arrayexpress
UnknownPlinabulin, an inhibitor of tubulin polymerization, targets KRAS signaling through disruption of endosomal recycling.
Not available
S-EPMC6439430 | biostudies-literature
TranscriptomicsGene expression of T47D-MTVL human breast cancer cells growing in normal conditions
Basal gene expression of T47D-MTVL human breast cancer cells growing in normal conditions Breast cancer cells T47D-MTVL cells were grown in rich media and total RNA was extracted to monitor basal gene expression
ORGANISM(S): Homo sapiens 
2014-02-04 | E-GEOD-49236 | biostudies-arrayexpress
TranscriptomicsDNA methylation profiles in primary cutaneous melanoma are associated with clinically significant pathologic features
We investigated whether methylation in primary melanomas is associated with tumor pathologic features or defines subgroups of primary melanomas 47 primary cutaneous melanomas were analyzed using the Illumina GoldenGate Cancer Panel I methylation array
ORGANISM(S): Homo sapiens 
2015-06-15 | E-GEOD-54623 | biostudies-arrayexpress
TranscriptomicsProteomic view of the Plasmodium falciparum life cycle
The completion of the Plasmodium falciparum clone 3D7 genome provides a basis on which to conduct comparative proteomics studies of this human pathogen. Here, we applied a high-throughput proteomics approach to identify new potential drug and vaccine targets and to better understand the biology of t...
ORGANISM(S): Plasmodium falciparum 3D7 
2002-12-22 | E-GEOD-92 | biostudies-arrayexpress
TranscriptomicsPancreatic Cancer 1
This is the experiment set used for a paper written in collaboration with Hopkins. It compares genes that are differentially expressed between normal pancreas, pancreatic cell lines and pancreatic adenocarcinoma. Pancreatic cancer is the fifth leading cause of cancer death in the United States. We u...
ORGANISM(S): Homo sapiens 
2005-11-23 | E-GEOD-3654 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of mouse littermate wild-type and Shh null E10.5 forelimbs [Illumina]
We wanted to identify differentially expressed genes in wild-type and Shh null E10.5 mouse forelimbs Used two wild-type technical replicates and two Shh null technical replicates UT-Genome and Analysis Facility
ORGANISM(S): Mus musculus 
2015-07-01 | E-GEOD-58645 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of cultured mouse wild-type E10.25 forelimbs in control or cyclopmaine containing media [SOLiD]
We wanted to identify differentially expressed genes in wild-type forelimbs and forelimbs briefly exposed to Shh signaling. E10.25 forelimbs were cultured in control media and media containing cyclopmaine (inhibits the Hedgehog pathway) Generated two wild-type (control) and two cyclopmaine biologic...
ORGANISM(S): Mus musculus 
2015-07-01 | E-GEOD-58664 | biostudies-arrayexpress
TranscriptomicsHi-C map of the three-dimensional genome organization
The spatial arrangement of interphase chromosomes in the nucleus is important for gene expression and genome function in animals and in plants. The recently developed Hi-C technology is an efficacious method to investigate genome packing. Here we present a detailed Hi-C map of the three-dimensional ...
ORGANISM(S): Arabidopsis thaliana 
2014-09-24 | E-MTAB-4438 | biostudies-arrayexpress
TranscriptomicsGene expression profiles induced by overexpression of PDEF in MCF10A mammary epithelial cell line
Recent studies suggest that PDEF is required for secretory cell differentiation in several epithelial tissues. To investigate PDEF in the mammary gland, we examined the effect of this transcription factor on gene expression using microarray based profiling of MCF-10A cells. These cells are non-trans...
ORGANISM(S): Homo sapiens 
2014-03-29 | E-GEOD-40986 | biostudies-arrayexpress
Sort   by:  
 Page size