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TranscriptomicsS. cerevisiae cells: control vs positive supercoiling accumulation in absence of telomere silencing after 0 and 120 min
Positive DNA helical stress accumulates in vivo by the unbalanced relaxation of positive and negative DNA supercoils in M-NM-^Ttop1, top2ts, pGPD:TopA yeast cells. The resulting overwinding of DNA greatly diminishes overall RNA synthesis. Here we show that whereas most genes reduce their transcript ...
ORGANISM(S): Saccharomyces cerevisiae 
2009-12-01 | E-GEOD-18241 | biostudies-arrayexpress
GenomicsGenome-wide analysis of GATA1, GATA2, RUNX1, FLI1 and SCL binding in primary human megakaryocytes
We have mapped the binding sites for the five key regulators GATA1, GATA2, RUNX1, FLI1 and TAL1/SCL in primary human megakaryocytes. Statistical analysis identified subsets of enriched as well as depleted combinatorial binding patterns. In particular simultaneous binding by all 5 factors was highly ...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-24674 | biostudies-arrayexpress
UnknownWELPSA: A natural catalyst of alkali and alkaline earth metals for the facile synthesis of tetrahydrobenzo[b]pyrans and pyrano[2,3-d]pyrimidinones as inhibitors of SARS-CoV-2.
Not available
S-EPMC8646655 | biostudies-literature
TranscriptomicsSaccharomyces cerevisiae cells: control vs positive supercoiling accumulation
This SuperSeries is composed of the following subset Series: GSE18240: Saccharomyces cerevisiae cells: control vs positive supercoiling accumulation after 0, 30 and 120 min GSE18241: S. cerevisiae cells: control vs positive supercoiling accumulation in absence of telomere silencing after 0 and 120 m...
ORGANISM(S): Saccharomyces cerevisiae 
2009-12-01 | E-GEOD-18242 | biostudies-arrayexpress
UnknownStaphylococcus aureus and Methicillin Resistant S. aureus in Nepalese Primates: Resistance to Antimicrobials, Virulence, and Genetic Lineages.
Not available
S-EPMC7601186 | biostudies-literature
TranscriptomicsThe transcriptional program controlled by Runx1 during early hematopoietic development
This SuperSeries is composed of the following subset Series: GSE29112: The transcriptional program controlled by Runx1 during early hematopoietic development (expression data) GSE29514: The transcriptional program controlled by Runx1 during early hematopoietic development (ChIP-seq data) Refer to in...
ORGANISM(S): Mus musculus 
2012-05-30 | E-GEOD-29515 | biostudies-arrayexpress
TranscriptomicsSaccharomyces cerevisiae cells: control vs positive supercoiling accumulation after 0, 30 and 120 min
Positive DNA helical stress accumulates in vivo by the unbalanced relaxation of positive and negative DNA supercoils in Δtop1, top2ts, pGPD:TopA yeast cells. The resulting overwinding of DNA greatly diminishes overall RNA synthesis. Here we show that whereas most genes reduce their transcript level...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-19 | E-GEOD-18240 | biostudies-arrayexpress
UnknownEffect of a Web-Based Heartfulness Program on the Mental Well-Being, Biomarkers, and Gene Expression Profile of Health Care Students: Randomized Controlled Trial.
Not available
S-EPMC11686021 | biostudies-literature
UnknownHQAlign: Aligning nanopore reads for SV detection using current-level modeling.
Not available
S-EPMC9882582 | biostudies-literature
TranscriptomicsThe transcriptional program controlled by Runx1 during early hematopoietic development (expression data)
Transcription factors have long been recognised as powerful regulators of mammalian development, yet it is largely unknown how individual key regulators operate within wider regulatory networks. Here we have used a combination of global gene expression and chromatin-immunoprecipitation approaches a...
ORGANISM(S): Mus musculus 
2012-05-29 | E-GEOD-29112 | biostudies-arrayexpress
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