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TranscriptomicsCyclin K and cyclin D1b are oncogenic in myeloma cells
To study the oncogenic potential of cyclin D1b in the context of mature B cells we generated several cell clones derived from LP-1 MM cell line expressing either cyclin D1b, Myc or cyclin K oncogenes. Transcriptomic analysis allowed us to describe several mechanisms of cyclin D1b- and K-mediated onc...
ORGANISM(S): Homo sapiens 
2010-04-23 | E-GEOD-15497 | biostudies-arrayexpress
TranscriptomicsTEAD4 occupied genes in differentiated C2C12 myoblasts
The TEAD (1-4) transcription factors comprise the conserved TEA/ATTS DNA binding domain recognising the MCAT element in the promoters of muscle-specific genes. Despite extensive genetic analysis, the function of TEAD factors in muscle differentiation has proved elusive due to redundancy amongst the ...
ORGANISM(S): Mus musculus 
2011-08-21 | E-GEOD-29208 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of heart samples of myotonic dystrophic (DM1) patients
Analysis of alternative splicing in heart (left ventricles) samples of 3 adult DM1 patients versus 3 adult controls PolyA RNA from left ventricles (heart) of 3 controls and 3 DM1 patients were analysed by massive parrallel sequencing
ORGANISM(S): Homo sapiens 
2015-04-14 | E-GEOD-67812 | biostudies-arrayexpress
TranscriptomicsGene expression in WT and Ikaros-deficient LSK cells
The Ikaros zink finger transcription factor is a critical regulator of the hematopietic system, and plays an important role in the regulation of the development and function of several blood cell lineages. We used microarrays to characterize how Ikaros deficieny affects global transcription in the h...
ORGANISM(S): Mus musculus 
2015-11-03 | E-GEOD-61147 | biostudies-arrayexpress
UnknownThe multistep road to ventilator-associated lung abscess: A retrospective study of S.aureus ventilator-associated pneumonia.
Not available
S-EPMC5738060 | biostudies-literature
UnknownCohesin forms fountains at active enhancers in C. elegans.
Not available
S-EPMC12820367 | biostudies-literature
GenomicsIkaros mediates gene silencing in T cells through Polycomb Repressive Complex 2 [ChIP-seq]
T cell development is accompanied by epigenetic changes that ensure the silencing of stem cell-related, and the activation of lymphocyte-specific programs. How transcription factors influence these changes remains unclear. We show that the Ikaros transcription factor interacts with the Polycomb Repr...
ORGANISM(S): Mus musculus 
2015-11-03 | E-GEOD-61148 | biostudies-arrayexpress
GenomicsGenome-wide mapping of Collier in vivo binding sites highlights its hierarchical position in different transcription regulatory networks
Collier, the single Drosophila COE (Collier/EBF/Olf-1) transcription factor, is required in several developmental processes, including head patterning and specification of muscle and neuron identity during embryogenesis. To identify direct Collier (Col) targets in different cell types, we used ChIP-...
ORGANISM(S): Drosophila melanogaster 
2015-08-03 | E-GEOD-67805 | biostudies-arrayexpress
UnknownCharacteristics and clinical assessment of unexplained sudden cardiac arrest in the real-world setting: focus on idiopathic ventricular fibrillation.
Not available
S-EPMC5982722 | biostudies-literature
UnknownPrognostic value of early EEG abnormalities in severe stroke patients requiring mechanical ventilation: a pre-planned analysis of the SPICE prospective multicenter study.
Not available
S-EPMC11119574 | biostudies-literature
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